About   Help   FAQ
Slc25a51 Gene Detail
Summary
  • Symbol
    Slc25a51
  • Name
    solute carrier family 25, member 51
  • Synonyms
    9130208E07Rik, D130005A03Rik, Mcart1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684984
    NCBI Gene: 230125
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:45395923-45408766 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 23.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    481 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684984
 protein coding gene Chr4:45395923-45408922 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033073
 protein coding gene Chr7:132560058-132563615 (+)
A/J MGP_AJ_G0028203
 protein coding gene Chr4:42065990-42081448 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0028223
 protein coding gene Chr4:42149844-42165410 (-)
C3H/HeJ MGP_C3HHeJ_G0027944
 protein coding gene Chr4:43681344-43693219 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028664
 protein coding gene Chr4:45272936-45287032 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025973
 protein coding gene Chr4:39450694-39464019 (-)
CAST/EiJ MGP_CASTEiJ_G0032100
 protein coding gene Chr7:124043246-124046527 (+)
CBA/J MGP_CBAJ_G0027910
 protein coding gene Chr4:46683444-46700747 (-)
DBA/2J MGP_DBA2J_G0028060
 protein coding gene Chr4:41965825-41979885 (-)
FVB/NJ MGP_FVBNJ_G0028027
 protein coding gene Chr4:41192698-41205917 (-)
LP/J MGP_LPJ_G0028159
 protein coding gene Chr4:43686908-43698663 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028051
 protein coding gene Chr4:49828712-49851820 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028699
 protein coding gene Chr4:43285030-43301110 (-)
PWK/PhJ MGP_PWKPhJ_G0027108
 protein coding gene Chr4:42033985-42049731 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026936
 protein coding gene Chr4:42807127-42808703 (-)
WSB/EiJ MGP_WSBEiJ_G0027461
 protein coding gene Chr4:43163164-43203424 (-)



Homology
more
  • Human Ortholog
    SLC25A51, solute carrier family 25 member 51
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A51, solute carrier family 25 member 51
  • Synonyms
    CG7943, MCART1
  • Links
    NCBI Gene ID: 92014
    neXtProt AC: NX_Q9H1U9
    UniProt: Q9H1U9

  • Chr Location
    9p13.2-p13.1; chr9:37877575-37904353 (-)  GRCh38
  • Human Ortholog
    SLC25A52, solute carrier family 25 member 52
  • Synonyms
    MCART2
  • Links
    NCBI Gene ID: 147407
    neXtProt AC: NX_Q3SY17
    UniProt: Q3SY17

  • Chr Location
    18q12.1; chr18:31759584-31760880 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045973 Ensembl Gene Model | MGI Sequence Detail 12844 C57BL/6J ±  kb
transcript ENSMUST00000107796 Ensembl | MGI Sequence Detail 4433 Not Applicable  
polypeptide ENSMUSP00000103425 Ensembl | MGI Sequence Detail 315 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000029735 mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51
    (term hierarchy)
  • InterPro Domains
    IPR023395 Mitochondrial carrier domain superfamily
    IPR052465 Mitochondrial NAD+ Carrier
    IPR018108 Mitochondrial substrate/solute carrier
  • GlyGen
    Q5HZI9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924920
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:345554 Fu Z, et al., The mitochondrial NAD(+) transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions. Metabolism. 2022 Aug 4;135:155275
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory