Zfp648 MGI Mouse Gene Detail - MGI:2685049

Symbol

Zfp648
Name

zinc finger protein 648
Synonyms

Gm10178, LOC207678

Feature Type

protein coding gene
IDs

MGI:2685049
NCBI Gene: 100503355
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr1:154076933-154081435 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 65.97 cM
Mapping Data

2 experiments

SNPs within 2kb

209 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685049	protein coding gene	Chr1:154076933-154088955 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016607	protein coding gene	Chr1:159084951-159089455 (+)
A/J	MGP_AJ_G0016588	protein coding gene	Chr1:152670796-152675371 (+)
AKR/J	MGP_AKRJ_G0016554	protein coding gene	Chr1:157395422-157399924 (+)
BALB/cJ	MGP_BALBcJ_G0016549	protein coding gene	Chr1:153209781-153214283 (+)
C3H/HeJ	MGP_C3HHeJ_G0016373	protein coding gene	Chr1:157514225-157518731 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017010	protein coding gene	Chr1:164569149-164573633 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014719	protein coding gene	Chr1:144934604-144939220 (+)
CAST/EiJ	MGP_CASTEiJ_G0015953	protein coding gene	Chr1:157023995-157028486 (+)
CBA/J	MGP_CBAJ_G0016348	protein coding gene	Chr1:170384922-170389440 (+)
DBA/2J	MGP_DBA2J_G0016454	protein coding gene	Chr1:151675695-151680173 (+)
FVB/NJ	MGP_FVBNJ_G0016452	protein coding gene	Chr1:150142836-150147338 (+)
LP/J	MGP_LPJ_G0016525	protein coding gene	Chr1:160220066-160224544 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016477	protein coding gene	Chr1:178004779-178009281 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017046	protein coding gene	Chr1:157189273-157193775 (+)
PWK/PhJ	MGP_PWKPhJ_G0015739	protein coding gene	Chr1:150741272-150745779 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015526	protein coding gene	Chr1:155949387-155954187 (+)
WSB/EiJ	MGP_WSBEiJ_G0016015	protein coding gene	Chr1:157258754-157263228 (+)

Human Ortholog

ZNF648, zinc finger protein 648

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZNF648, zinc finger protein 648
Links

HGNC:18190

NCBI Gene ID: 127665

neXtProt AC: NX_Q5T619

UniProt: Q5T619
Chr Location

1q25.3; chr1:182054570-182069646 (-) GRCh38

MGI Vertebrate Homology

Zfp648 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: ZNF648
Gene Tree

Zfp648

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

2
Endonuclease-mediated

2
Genomic Mutations

2 involving Zfp648
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

26 strains or lines available

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All GO Annotations

3
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

3

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

29
RefSeq

4
UniProt

1
CCDS

CCDS56646.1

Ensembl

ENSMUSG00000066797 (Evidence)
NCBI Gene

100503355

			Length	Strain/Species	Flank
genomic	ENSMUSG00000066797	Ensembl Gene Model \| MGI Sequence Detail	4503	C57BL/6J	± kb
transcript	ENSMUST00000086195	Ensembl \| MGI Sequence Detail	1892	Not Applicable
polypeptide	ENSMUSP00000083370	Ensembl \| MGI Sequence Detail	525	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 3

cDNA 3

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MGI:3641727

Summaries

All 16

Gene Ontology 1

Phenotypes 4
Earliest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Zfp648:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr9514	Chr1:154077298-154077306 (+)	369 bp
Tssr9515	Chr1:154077311-154077323 (+)	384 bp
Tssr9516	Chr1:154080625-154080636 (+)	3,698 bp
Tssr9517	Chr1:154080652-154080665 (+)	3,726 bp
Tssr9518	Chr1:154080893-154080895 (+)	3,961 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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