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Ccdc170 Gene Detail
Summary
  • Symbol
    Ccdc170
  • Name
    coiled-coil domain containing 170
  • Synonyms
    Gm221, LOC237250
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685067
    NCBI Gene: 100504234
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:4432502-4512231 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 2.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2484 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685067
protein coding gene Chr10:4432312-4514498 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016980
protein coding gene Chr10:1484179-1581461 (+)
A/J MGP_AJ_G0016958
protein coding gene Chr10:1403386-1492481 (+)
AKR/J MGP_AKRJ_G0016923
protein coding gene Chr10:1396052-1487523 (+)
BALB/cJ MGP_BALBcJ_G0016916
protein coding gene Chr10:1373501-1456356 (+)
C3H/HeJ MGP_C3HHeJ_G0016741
protein coding gene Chr10:1496078-1580787 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017379
protein coding gene Chr10:1526509-1614386 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015085
protein coding gene Chr10:1228613-1308958 (+)
CAST/EiJ MGP_CASTEiJ_G0016323
protein coding gene Chr10:1542403-1630150 (+)
CBA/J MGP_CBAJ_G0016713
protein coding gene Chr10:1574847-1665129 (+)
DBA/2J MGP_DBA2J_G0016821
protein coding gene Chr10:1408179-1487555 (+)
FVB/NJ MGP_FVBNJ_G0016816
protein coding gene Chr10:1371459-1450829 (+)
LP/J MGP_LPJ_G0016896
protein coding gene Chr10:1475290-1556539 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016847
protein coding gene Chr10:1464925-1560617 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017416
protein coding gene Chr10:1417665-1509605 (+)
PWK/PhJ MGP_PWKPhJ_G0016109
protein coding gene Chr10:1407661-1491849 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015890
protein coding gene Chr10:1607732-1693257 (+)
WSB/EiJ MGP_WSBEiJ_G0016384
protein coding gene Chr10:1481004-1572571 (+)



Homology
more
  • Human Ortholog
    CCDC170, coiled-coil domain containing 170
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC170, coiled-coil domain containing 170
  • Synonyms
    bA282P11.1, C6orf97
  • Links
    NCBI Gene ID: 80129
    neXtProt AC: NX_Q8IYT3
    UniProt: Q8IYT3

  • Chr Location
    6q25.1; chr6:151494017-151621193 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019767 Ensembl Gene Model | MGI Sequence Detail 79730 C57BL/6J ±  kb
transcript ENSMUST00000138112 Ensembl | MGI Sequence Detail 3350 Not Applicable  
polypeptide ENSMUSP00000115997 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR039139 Coiled-coil domain-containing protein 170-like
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory