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Prss47 Gene Detail
Summary
  • Symbol
    Prss47
  • Name
    serine protease 47
  • Synonyms
    Gm274, LOC218304
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685120
    NCBI Gene: 218304
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:65192420-65200574 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 34.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    321 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685120
protein coding gene Chr13:65192420-65200685 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020684
protein coding gene Chr13:65059608-65067707 (-)
A/J MGP_AJ_G0020638
protein coding gene Chr13:62687331-62695488 (-)
AKR/J MGP_AKRJ_G0020615
protein coding gene Chr13:64762753-64770847 (-)
BALB/cJ MGP_BALBcJ_G0020636
protein coding gene Chr13:63119092-63127203 (-)
C3H/HeJ MGP_C3HHeJ_G0020431
protein coding gene Chr13:64290087-64298221 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021072
protein coding gene Chr13:67184133-67192210 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018648
protein coding gene Chr13:60350301-60358451 (-)
CAST/EiJ MGP_CASTEiJ_G0019948
protein coding gene Chr13:64332697-64340776 (-)
CBA/J MGP_CBAJ_G0020391
protein coding gene Chr13:69741056-69755324 (-)
DBA/2J MGP_DBA2J_G0020516
protein coding gene Chr13:62529316-62537453 (-)
FVB/NJ MGP_FVBNJ_G0020495
protein coding gene Chr13:61605895-61614010 (-)
LP/J MGP_LPJ_G0020590
protein coding gene Chr13:65340058-65348205 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020524
protein coding gene Chr13:68671103-68679290 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021114
protein coding gene Chr13:64083842-64091982 (-)
PWK/PhJ MGP_PWKPhJ_G0019702
protein coding gene Chr13:62091719-62100032 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019528
protein coding gene Chr13:62269260-62279090 (-)
WSB/EiJ MGP_WSBEiJ_G0020008
protein coding gene Chr13:64550116-64558199 (-)



Homology
more
  • Human Ortholog
    PRSS47P, serine protease 47, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS47P, serine protease 47, pseudogene
  • Synonyms
    PRSS47
  • Links
    NCBI Gene ID: 138652
    UniProt: A8MTI9

  • Chr Location
    9q22.31; chr9:92177163-92191156 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000090658 Ensembl Gene Model | MGI Sequence Detail 8155 C57BL/6J ±  kb
    transcript ENSMUST00000203968 Ensembl | MGI Sequence Detail 1353 Not Applicable  
    polypeptide ENSMUSP00000145196 Ensembl | MGI Sequence Detail 395 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR001314 Peptidase S1A, chymotrypsin family
      IPR009003 Peptidase S1, PA clan
      IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
      IPR001254 Serine proteases, trypsin domain
      IPR033116 Serine proteases, trypsin family, serine active site
    References
    more
    • Summaries
      All 15
      Phenotypes 7
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory