Ppp1r26 MGI Mouse Gene Detail - MGI:2685193 - protein phosphatase 1, regulatory subunit 26

Symbol

Ppp1r26
Name

protein phosphatase 1, regulatory subunit 26
Synonyms

LOC241289

Feature Type

protein coding gene
IDs

MGI:2685193
NCBI Gene: 241289
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr2:28336812-28345520 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 19.38 cM
Mapping Data

1 experiment

SNPs within 2kb

279 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685193	protein coding gene	Chr2:28336613-28345520 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025520	protein coding gene	Chr2:26502317-26511030 (+)
A/J	MGP_AJ_G0025497	protein coding gene	Chr2:25501666-25510343 (+)
AKR/J	MGP_AKRJ_G0025467	protein coding gene	Chr2:26345989-26354620 (+)
BALB/cJ	MGP_BALBcJ_G0025493	protein coding gene	Chr2:25620012-25629793 (+)
C3H/HeJ	MGP_C3HHeJ_G0025254	protein coding gene	Chr2:26269458-26277943 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025937	protein coding gene	Chr2:27401361-27412758 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023348	protein coding gene	Chr2:24309901-24318482 (+)
CAST/EiJ	MGP_CASTEiJ_G0024717	protein coding gene	Chr2:26166934-26177870 (+)
CBA/J	MGP_CBAJ_G0025232	protein coding gene	Chr2:28335749-28345304 (+)
DBA/2J	MGP_DBA2J_G0025365	protein coding gene	Chr2:25311381-25320091 (+)
FVB/NJ	MGP_FVBNJ_G0025327	protein coding gene	Chr2:25089024-25097720 (+)
LP/J	MGP_LPJ_G0025451	protein coding gene	Chr2:26453547-26462252 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025358	protein coding gene	Chr2:28335773-28346137 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025996	protein coding gene	Chr2:26257388-26269425 (+)
PWK/PhJ	MGP_PWKPhJ_G0024465	protein coding gene	Chr2:25115060-25123986 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024265	protein coding gene	Chr2:26395838-26404428 (+)
WSB/EiJ	MGP_WSBEiJ_G0024786	protein coding gene	Chr2:26395021-26403718 (+)

Human Ortholog

PPP1R26, protein phosphatase 1 regulatory subunit 26

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PPP1R26, protein phosphatase 1 regulatory subunit 26
Synonyms

KIAA0649, NRBE3
Links

HGNC:29089

NCBI Gene ID: 9858

neXtProt AC: NX_Q5T8A7

UniProt: Q5T8A7
Chr Location

9q34.3; chr9:135479066-135488893 (+) GRCh38

MGI Vertebrate Homology

Ppp1r26 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PPP1R26
Gene Tree

Ppp1r26

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
5 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Targeted

4
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

24 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

2
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

750
Tissues

37
cDNA Data

28
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ppp1r26

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All Sequences

52
RefSeq

20
UniProt

1
CCDS

CCDS15836.1

Ensembl

ENSMUSG00000035829 (Evidence)
NCBI Gene

241289

			Length	Strain/Species	Flank
genomic	ENSMUSG00000035829	Ensembl Gene Model \| MGI Sequence Detail	8709	C57BL/6J	± kb
transcript	ENSMUST00000189694	Ensembl \| MGI Sequence Detail	5463	Not Applicable
polypeptide	ENSMUSP00000139546	Ensembl \| MGI Sequence Detail	1163	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000030603 protein phosphatase 1 regulatory subunit 26

(term hierarchy)
InterPro Domains

IPR026130 Protein phosphatase 1 regulatory subunit 26

IPR031474 Protein phosphatase 1 regulatory subunit 26, N-terminal domain

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All nucleic 28

cDNA 28

Microarray probesets 1

Summaries

All 22

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 5
Earliest

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ppp1r26:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr16926	Chr2:28336843-28336890 (+)	55 bp
Tssr16927	Chr2:28336971-28337004 (+)	176 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24