Spdye4c Gene Detail

Summary

• Symbol
  Spdye4c
• Name
  speedy/RINGO cell cycle regulator family, member E4C
• Synonyms
  Gm355, LOC241634

• Feature Type
  protein coding gene
• IDs
  MGI:2685201
  NCBI Gene: 241634
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr2:128433129-128440384 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 62.63 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  250 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685201	protein coding gene	Chr2:128433121-128443483 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0026473	protein coding gene	Chr2:131931523-131941060 (+)
A/J	MGP_AJ_G0026437	protein coding gene	Chr2:126592947-126600015 (+)
AKR/J	MGP_AKRJ_G0026412	protein coding gene	Chr2:130189291-130198655 (+)
BALB/cJ	MGP_BALBcJ_G0026449	protein coding gene	Chr2:126855468-126863254 (+)
C3H/HeJ	MGP_C3HHeJ_G0026192	protein coding gene	Chr2:130695630-130703240 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0026894	protein coding gene	Chr2:136059318-136066417 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0024271	protein coding gene	Chr2:121418049-121424530 (+)
CAST/EiJ	MGP_CASTEiJ_G0025653	protein coding gene	Chr2:130932128-130939230 (+)
CBA/J	MGP_CBAJ_G0026172	protein coding gene	Chr2:141083680-141090473 (+)
DBA/2J	MGP_DBA2J_G0026306	protein coding gene	Chr2:125984088-125991224 (+)
FVB/NJ	MGP_FVBNJ_G0026270	protein coding gene	Chr2:124633588-124640500 (+)
LP/J	MGP_LPJ_G0026411	protein coding gene	Chr2:132164961-132172792 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0026290	protein coding gene	Chr2:145035355-145043784 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0026949	protein coding gene	Chr2:130214025-130223250 (+)
PWK/PhJ	MGP_PWKPhJ_G0025389	protein coding gene	Chr2:125555743-125563799 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0025191	protein coding gene	Chr2:129329408-129338776 (+)
WSB/EiJ	MGP_WSBEiJ_G0025727	protein coding gene	Chr2:131131312-131140183 (+)

Homology

• MGI Vertebrate Homology
  Spdye4c stringent orthology
  1 mouse;1 rat
  
• Gene Tree
  Spdye4c
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Spdye4c
• Incidental Mutations
  APF
• Find Mice (IMSR)
  14 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  7
• UniProt
  1
• CCDS
  CCDS79844.1

• Ensembl
  ENSMUSG00000074812 (Evidence)
• NCBI Gene
  241634

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000074812	Ensembl Gene Model | MGI Sequence Detail	7256	C57BL/6J
transcript	ENSMUST00000155430	Ensembl | MGI Sequence Detail	1383	Not Applicable
polypeptide	ENSMUSP00000117916	Ensembl | MGI Sequence Detail	339	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR020984 Cell cycle regulatory protein Speedy

References

• Summaries
  All 14

  Gene Ontology 1

  Phenotypes 5
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Spdye4c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr20058	Chr2:128433125-128433143 (+)	5 bp
Tssr20059	Chr2:128433153-128433164 (+)	30 bp