Tigd4 MGI Mouse Gene Detail - MGI:2685264 - tigger transposable element derived 4

Symbol

Tigd4
Name

tigger transposable element derived 4
Synonyms

C130063O11Rik, Tigd4

Feature Type

protein coding gene
IDs

MGI:2685264
NCBI Gene: 403175
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr3:84500881-84504339 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 37.70 cM
Mapping Data

1 experiment

SNPs within 2kb

132 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685264	protein coding gene	Chr3:84500881-84504339 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027345	protein coding gene	Chr3:84516409-84519867 (+)
A/J	MGP_AJ_G0027309	protein coding gene	Chr3:81702189-81705647 (+)
AKR/J	MGP_AKRJ_G0027275	protein coding gene	Chr3:83635535-83638994 (+)
BALB/cJ	MGP_BALBcJ_G0027318	protein coding gene	Chr3:81780510-81783969 (+)
C3H/HeJ	MGP_C3HHeJ_G0027062	protein coding gene	Chr3:83944837-83948295 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027764	protein coding gene	Chr3:87670590-87674048 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025117	protein coding gene	Chr3:77380284-77383752 (+)
CAST/EiJ	MGP_CASTEiJ_G0026509	protein coding gene	Chr3:84130777-84134242 (+)
CBA/J	MGP_CBAJ_G0027037	protein coding gene	Chr3:90611477-90614935 (+)
DBA/2J	MGP_DBA2J_G0027173	protein coding gene	Chr3:81217824-81221283 (+)
FVB/NJ	MGP_FVBNJ_G0027141	protein coding gene	Chr3:79500338-79503796 (+)
LP/J	MGP_LPJ_G0027281	protein coding gene	Chr3:85493829-85497287 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027160	protein coding gene	Chr3:96945300-96948758 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027822	protein coding gene	Chr3:83432598-83436056 (+)
PWK/PhJ	MGP_PWKPhJ_G0026243	protein coding gene	Chr3:81000061-81003519 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026059	protein coding gene	Chr3:82613338-82616800 (+)
WSB/EiJ	MGP_WSBEiJ_G0026587	protein coding gene	Chr3:83794671-83798130 (+)

Human Ortholog

TIGD4, tigger transposable element derived 4

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TIGD4, tigger transposable element derived 4
Links

HGNC:18335

NCBI Gene ID: 201798

neXtProt AC: NX_Q8IY51

UniProt: Q8IY51
Chr Location

4q31.3; chr4:152769354-152779730 (-) GRCh38

MGI Vertebrate Homology

Tigd4 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TIGD4
Gene Tree

Tigd4

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References

1 with disease annotations

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Radiation induced

1
Genomic Mutations

2 involving Tigd4
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

23 strains or lines available

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All GO Annotations

4
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

740
Tissues

3
cDNA Data

3
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

26
RefSeq

2
UniProt

1
CCDS

CCDS17439.1

Ensembl

ENSMUSG00000047819 (Evidence)
NCBI Gene

403175

			Length	Strain/Species	Flank
genomic	403175	NCBI Gene Model \| MGI Sequence Detail	3459	C57BL/6J	± kb
transcript	NM_207278	RefSeq \| MGI Sequence Detail	3459	Not Specified
polypeptide	Q8BUZ3	UniProt \| EBI \| MGI Sequence Detail	513	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000016334 tigger transposable element-derived protein 4

(term hierarchy)
InterPro Domains

IPR050863 Centromere and Transposable Element-Derived Protein

IPR004875 DDE superfamily endonuclease domain

IPR007889 DNA binding HTH domain, Psq-type

IPR009057 Homeobox-like domain superfamily

IPR006600 HTH CenpB-type DNA-binding domain

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All nucleic 3

cDNA 3

Microarray probesets 1

Summaries

All 21

Developmental Gene Expression 2

Diseases 1

Gene Ontology 3

Phenotypes 4
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Tigd4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr29737	Chr3:84500854-84500870 (+)	-19 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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