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Plcxd1 Gene Detail
Summary
  • Symbol
    Plcxd1
  • Name
    phosphatidylinositol-specific phospholipase C, X domain containing 1
  • Synonyms
    A330045H12Rik, LOC231597
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685422
    NCBI Gene: 403178
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:110247835-110253819 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.30 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685422
 protein coding gene Chr5:110247661-110253819 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029876
 protein coding gene Chr5:112521087-112527035 (+)
A/J MGP_AJ_G0029842
 protein coding gene Chr5:108177475-108183465 (+)
AKR/J MGP_AKRJ_G0029780
 protein coding gene Chr5:111621680-111627586 (+)
BALB/cJ MGP_BALBcJ_G0029853
 protein coding gene Chr5:109547814-109553760 (+)
C3H/HeJ MGP_C3HHeJ_G0029573
 protein coding gene Chr5:112045164-112052211 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030306
 protein coding gene Chr5:116980623-116986556 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027535
 protein coding gene Chr5:103004964-103011070 (+)
CAST/EiJ MGP_CASTEiJ_G0028981
 protein coding gene Chr5:110911462-110919349 (+)
CBA/J MGP_CBAJ_G0029540
 protein coding gene Chr5:121378337-121384350 (+)
DBA/2J MGP_DBA2J_G0029690
 protein coding gene Chr5:108240617-108246680 (+)
FVB/NJ MGP_FVBNJ_G0029647
 protein coding gene Chr5:106920245-106926420 (+)
LP/J MGP_LPJ_G0029778
 protein coding gene Chr5:113092956-113099255 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029678
 protein coding gene Chr5:126036161-126042273 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030347
 protein coding gene Chr5:111051322-111057355 (+)
PWK/PhJ MGP_PWKPhJ_G0028695
 protein coding gene Chr5:106836361-106842378 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028533
 protein coding gene Chr5:108521694-108527689 (+)
WSB/EiJ MGP_WSBEiJ_G0029057
 protein coding gene Chr5:111503000-111508955 (+)



Homology
more
  • Human Ortholog
    PLCXD1, phosphatidylinositol specific phospholipase C X domain containing 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLCXD1, phosphatidylinositol specific phospholipase C X domain containing 1
  • Synonyms
    LL0XNC01-136G2.1
  • Links
    NCBI Gene ID: 55344
    neXtProt AC: NX_Q9NUJ7
    UniProt: Q9NUJ7

  • Chr Location
    XY;Y
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064247 Ensembl Gene Model | MGI Sequence Detail 5985 C57BL/6J ±  kb
transcript ENSMUST00000086687 Ensembl | MGI Sequence Detail 1346 Not Applicable  
polypeptide ENSMUSP00000083892 Ensembl | MGI Sequence Detail 357 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000030757 PI-PLC X domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
    IPR051057 Phosphoinositide phospholipase C domain-containing protein
    IPR042158 PI-PLC X domain-containing protein 1/2/3
    IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:203736 Goldsworthy M, et al., Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice. PLoS One. 2013;8(6):e61870
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory