About   Help   FAQ
Igfl3 Gene Detail
Summary
  • Symbol
    Igfl3
  • Name
    IGF-like family member 3
  • Synonyms
    Igfl, LOC232925
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685426
    NCBI Gene: 232925
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:17910419-17915787 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    291 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685426
 protein coding gene Chr7:17910419-17915787 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031737
 protein coding gene Chr7:15985845-15991259 (+)
A/J MGP_AJ_G0031709
 protein coding gene Chr7:15676330-15681689 (+)
AKR/J MGP_AKRJ_G0031634
 protein coding gene Chr7:16050779-16056129 (+)
BALB/cJ MGP_BALBcJ_G0031716
 protein coding gene Chr7:15914802-15920169 (+)
C3H/HeJ MGP_C3HHeJ_G0031438
 protein coding gene Chr7:16360631-16366001 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032182
 protein coding gene Chr7:16841739-16847082 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029257
 protein coding gene Chr7:17381052-17386922 (+)
CAST/EiJ MGP_CASTEiJ_G0030789
 protein coding gene Chr7:12857654-12863093 (+)
CBA/J MGP_CBAJ_G0031397
 protein coding gene Chr7:17407561-17412957 (+)
DBA/2J MGP_DBA2J_G0031553
 protein coding gene Chr7:15589448-15594800 (+)
FVB/NJ MGP_FVBNJ_G0031509
 protein coding gene Chr7:15558408-15563742 (+)
LP/J MGP_LPJ_G0031638
 protein coding gene Chr7:16257555-16262945 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031544
 protein coding gene Chr7:17326106-17331468 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032211
 protein coding gene Chr7:15818621-15823977 (+)
PWK/PhJ MGP_PWKPhJ_G0030512
 protein coding gene Chr7:12969853-12976037 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030339
 protein coding gene Chr7:10686225-10692147 (+)
WSB/EiJ MGP_WSBEiJ_G0030885
 protein coding gene Chr7:15942819-15948151 (+)



Homology
more
  • Human Ortholog
    IGFL2, IGF like family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGFL2, IGF like family member 2
  • Synonyms
    UNQ645, VPRI645
  • Links
    NCBI Gene ID: 147920
    neXtProt AC: NX_Q6UWQ7
    UniProt: Q6UWQ7

  • Chr Location
    19q13.32; chr19:46078513-46215362 (+)  GRCh38
  • Human Ortholog
    IGFL3, IGF like family member 3
  • Synonyms
    UNQ483
  • Links
    NCBI Gene ID: 388555
    neXtProt AC: NX_Q6UXB1
    UniProt: Q6UXB1

  • Chr Location
    19q13.32; chr19:46120067-46124688 (-)  GRCh38
  • Human Ortholog
    IGFL4, IGF like family member 4
  • Links
    NCBI Gene ID: 444882
    neXtProt AC: NX_Q6B9Z1
    UniProt: Q6B9Z1

  • Chr Location
    19q13.32; chr19:46039182-46077629 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    16
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232925 NCBI Gene Model | MGI Sequence Detail 5369 C57BL/6J ±  kb
transcript NM_001003393 RefSeq | MGI Sequence Detail 575 Not Specified  
polypeptide Q6B9Z0 UniProt | EBI | MGI Sequence Detail 140 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR032744 Insulin growth factor-like family
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory