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Pla2g4f Gene Detail
Summary
  • Symbol
    Pla2g4f
  • Name
    phospholipase A2, group IVF
  • Synonyms
    4732472I07Rik, Pla2zeta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685493
    NCBI Gene: 271844
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120130438-120144646 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.31 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685493
 protein coding gene Chr2:120130433-120144646 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026363
 protein coding gene Chr2:123161400-123175595 (-)
A/J MGP_AJ_G0026324
 protein coding gene Chr2:118111636-118125841 (-)
AKR/J MGP_AKRJ_G0026303
 protein coding gene Chr2:121409999-121424232 (-)
BALB/cJ MGP_BALBcJ_G0026337
 protein coding gene Chr2:118356991-118371177 (-)
C3H/HeJ MGP_C3HHeJ_G0026083
 protein coding gene Chr2:121885848-121900057 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026784
 protein coding gene Chr2:127176773-127190975 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024164
 protein coding gene Chr2:113131135-113144931 (-)
CAST/EiJ MGP_CASTEiJ_G0025545
 protein coding gene Chr2:122198697-122212896 (-)
CBA/J MGP_CBAJ_G0026059
 protein coding gene Chr2:131621460-131639090 (-)
DBA/2J MGP_DBA2J_G0026198
 protein coding gene Chr2:117503977-117518169 (-)
FVB/NJ MGP_FVBNJ_G0026160
 protein coding gene Chr2:116340039-116354214 (-)
LP/J MGP_LPJ_G0026299
 protein coding gene Chr2:123419544-123434771 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026179
 protein coding gene Chr2:135937700-135951897 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026839
 protein coding gene Chr2:121535262-121549471 (-)
PWK/PhJ MGP_PWKPhJ_G0025281
 protein coding gene Chr2:117104999-117119549 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025080
 protein coding gene Chr2:120726157-120740184 (-)
WSB/EiJ MGP_WSBEiJ_G0025614
 protein coding gene Chr2:122372847-122387271 (-)



Homology
more
  • Human Ortholog
    PLA2G4F, phospholipase A2 group IVF
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLA2G4F, phospholipase A2 group IVF
  • Synonyms
    PLA2G4FZ
  • Links
    NCBI Gene ID: 255189
    neXtProt AC: NX_Q68DD2
    UniProt: Q68DD2

  • Chr Location
    15q15.1; chr15:42139034-42156636 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Lung fibroblasts from homozygous mutant mice show a normal response to the calcium ionophore A23187.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046971 Ensembl Gene Model | MGI Sequence Detail 14209 C57BL/6J ±  kb
    transcript ENSMUST00000054651 Ensembl | MGI Sequence Detail 3116 Not Applicable  
    polypeptide ENSMUSP00000062607 Ensembl | MGI Sequence Detail 855 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory