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Stkld1 Gene Detail
Summary
  • Symbol
    Stkld1
  • Name
    serine/threonine kinase-like domain containing 1
  • Synonyms
    Gm711, LOC279029
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685557
    NCBI Gene: 279029
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26824059-26843508 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    500 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685557
 protein coding gene Chr2:26823533-26843508 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025503
 protein coding gene Chr2:24905762-24926631 (+)
A/J MGP_AJ_G0025480
 protein coding gene Chr2:23961578-23981521 (+)
AKR/J MGP_AKRJ_G0025450
 protein coding gene Chr2:24742129-24762107 (+)
BALB/cJ MGP_BALBcJ_G0025476
 protein coding gene Chr2:24079911-24099294 (+)
C3H/HeJ MGP_C3HHeJ_G0025237
 protein coding gene Chr2:24680875-24705265 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025920
 protein coding gene Chr2:25747522-25768737 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023331
 protein coding gene Chr2:22800560-22820485 (+)
CAST/EiJ MGP_CASTEiJ_G0024700
 protein coding gene Chr2:24561020-24583680 (+)
CBA/J MGP_CBAJ_G0025215
 protein coding gene Chr2:26641950-26666323 (+)
DBA/2J MGP_DBA2J_G0025348
 protein coding gene Chr2:23778840-23802969 (+)
FVB/NJ MGP_FVBNJ_G0025310
 protein coding gene Chr2:23536995-23556904 (+)
LP/J MGP_LPJ_G0025434
 protein coding gene Chr2:24851124-24871662 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025341
 protein coding gene Chr2:26700181-26719786 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025979
 protein coding gene Chr2:24684374-24704143 (+)
PWK/PhJ MGP_PWKPhJ_G0024448
 protein coding gene Chr2:23572211-23592092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024248
 protein coding gene Chr2:24835871-24855249 (+)
WSB/EiJ MGP_WSBEiJ_G0024769
 protein coding gene Chr2:24804778-24825565 (+)



Homology
more
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
  • Synonyms
    C9orf96, SgK071, Sk521
  • Links
    NCBI Gene ID: 169436
    neXtProt AC: NX_Q8NE28
    UniProt: Q8NE28

  • Chr Location
    9q34.2; chr9:133376366-133406096 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049897 Ensembl Gene Model | MGI Sequence Detail 19450 C57BL/6J ±  kb
transcript ENSMUST00000055406 Ensembl | MGI Sequence Detail 2169 Not Applicable  
polypeptide ENSMUSP00000062967 Ensembl | MGI Sequence Detail 662 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory