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Wmp Gene Detail
Summary
  • Symbol
    Wmp
  • Name
    WAVE homology in membrane protrusions
  • Synonyms
    Gm732, Whimp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685578
    NCBI Gene: 213450
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:106989341-106992042 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 47.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685578
 protein coding gene ChrX:106989341-106992071 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036018
 protein coding gene ChrX:104804987-104807717 (-)
A/J MGP_AJ_G0035997
 protein coding gene ChrX:104614742-104617476 (-)
AKR/J MGP_AKRJ_G0035916
 protein coding gene ChrX:107922228-107924958 (-)
BALB/cJ MGP_BALBcJ_G0035988
 protein coding gene ChrX:103366004-103368734 (-)
C3H/HeJ MGP_C3HHeJ_G0035694
 protein coding gene ChrX:105261082-105263812 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036514
 protein coding gene ChrX:107831590-107834320 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033342
 protein coding gene ChrX:101827860-101830593 (-)
CAST/EiJ MGP_CASTEiJ_G0034981
 protein coding gene ChrX:89340048-89342779 (-)
CBA/J MGP_CBAJ_G0035670
 protein coding gene ChrX:111218079-111220809 (-)
DBA/2J MGP_DBA2J_G0035824
 protein coding gene ChrX:103841496-103844226 (-)
FVB/NJ MGP_FVBNJ_G0035764
 protein coding gene ChrX:103203918-103206648 (-)
LP/J MGP_LPJ_G0035916
 protein coding gene ChrX:105774103-105776833 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035795
 protein coding gene ChrX:116085557-116088287 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036541
 protein coding gene ChrX:104345243-104347973 (-)
PWK/PhJ MGP_PWKPhJ_G0034677
 protein coding gene ChrX:86863717-86866447 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034506
 protein coding gene ChrX:90167914-90170633 (-)
WSB/EiJ MGP_WSBEiJ_G0035119
 protein coding gene ChrX:103127748-103130478 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 213450 NCBI Gene Model | MGI Sequence Detail 2702 C57BL/6J ±  kb
transcript NM_001033252 RefSeq | MGI Sequence Detail 1661 C57BL/6  
polypeptide NP_001028424 RefSeq | MGI Sequence Detail 516 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR003124 WH2 domain
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
Other
Accession IDs
less
MGI:6438183
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:289916 Kabrawala S, et al., WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility. PLoS Genet. 2020 Mar;16(3):e1008694
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory