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Serpina11 Gene Detail
Summary
  • Symbol
    Serpina11
  • Name
    serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
  • Synonyms
    LOC380780
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685741
    NCBI Gene: 380780
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:103946502-103956216 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 52.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    431 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685741
 protein coding gene Chr12:103946502-103956227 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020063
 protein coding gene Chr12:105728042-105739187 (-)
A/J MGP_AJ_G0020017
 protein coding gene Chr12:101742072-101752775 (-)
AKR/J MGP_AKRJ_G0019995
 protein coding gene Chr12:104576964-104586798 (-)
BALB/cJ MGP_BALBcJ_G0020003
 protein coding gene Chr12:102033945-102043632 (-)
C3H/HeJ MGP_C3HHeJ_G0019807
 protein coding gene Chr12:105107000-105117641 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020450
 protein coding gene Chr12:109047077-109058325 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018066
 protein coding gene Chr12:98414099-98423889 (-)
CAST/EiJ MGP_CASTEiJ_G0019347
 protein coding gene Chr12:99833407-99844503 (-)
CBA/J MGP_CBAJ_G0019774
 protein coding gene Chr12:113058064-113071675 (-)
DBA/2J MGP_DBA2J_G0019890
 protein coding gene Chr12:101157984-101167789 (-)
FVB/NJ MGP_FVBNJ_G0019876
 protein coding gene Chr12:99964171-99974343 (-)
LP/J MGP_LPJ_G0019965
 protein coding gene Chr12:105570429-105580192 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019914
 protein coding gene Chr12:116525770-116536779 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020478
 protein coding gene Chr12:104086628-104096347 (-)
PWK/PhJ MGP_PWKPhJ_G0019111
 protein coding gene Chr12:95719910-95729914 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018911
 protein coding gene Chr12:98286391-98298204 (-)
WSB/EiJ MGP_WSBEiJ_G0019406
 protein coding gene Chr12:104931031-104945517 (-)



Homology
more
  • Human Ortholog
    SERPINA11, serpin family A member 11
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINA11, serpin family A member 11
  • Links
    NCBI Gene ID: 256394
    neXtProt AC: NX_Q86U17
    UniProt: Q86U17

  • Chr Location
    14q32.13; chr14:94442464-94452800 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    46
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063232 Ensembl Gene Model | MGI Sequence Detail 9715 C57BL/6J ±  kb
transcript ENSMUST00000074693 Ensembl | MGI Sequence Detail 1447 Not Applicable  
polypeptide ENSMUSP00000074258 Ensembl | MGI Sequence Detail 427 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory