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Zfp408 Gene Detail
Summary
  • Symbol
    Zfp408
  • Name
    zinc finger protein 408
  • Synonyms
    LOC381410
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685857
    NCBI Gene: 381410
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:91474014-91480136 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685857
 protein coding gene Chr2:91473101-91480372 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026153
 protein coding gene Chr2:92993211-92999375 (-)
A/J MGP_AJ_G0026114
 protein coding gene Chr2:89263278-89269408 (-)
AKR/J MGP_AKRJ_G0026095
 protein coding gene Chr2:91731796-91737840 (-)
BALB/cJ MGP_BALBcJ_G0026123
 protein coding gene Chr2:89447284-89453376 (-)
C3H/HeJ MGP_C3HHeJ_G0025874
 protein coding gene Chr2:92014293-92020355 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026574
 protein coding gene Chr2:96245973-96252098 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023965
 protein coding gene Chr2:85760870-85766923 (-)
CAST/EiJ MGP_CASTEiJ_G0025339
 protein coding gene Chr2:92561941-92569468 (-)
CBA/J MGP_CBAJ_G0025852
 protein coding gene Chr2:99550010-99556123 (-)
DBA/2J MGP_DBA2J_G0025988
 protein coding gene Chr2:88866194-88872074 (-)
FVB/NJ MGP_FVBNJ_G0025951
 protein coding gene Chr2:87964944-87970845 (-)
LP/J MGP_LPJ_G0026092
 protein coding gene Chr2:93210562-93216696 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025977
 protein coding gene Chr2:102568964-102575141 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026628
 protein coding gene Chr2:91805186-91811322 (-)
PWK/PhJ MGP_PWKPhJ_G0025074
 protein coding gene Chr2:88598216-88604325 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024875
 protein coding gene Chr2:91387419-91392307 (-)
WSB/EiJ MGP_WSBEiJ_G0025406
 protein coding gene Chr2:92405228-92411364 (-)



Homology
more
  • Human Ortholog
    ZNF408, zinc finger protein 408
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF408, zinc finger protein 408
  • Synonyms
    EVR6, RP72
  • Links
    NCBI Gene ID: 79797
    neXtProt AC: NX_Q9H9D4
    UniProt: Q9H9D4

  • Chr Location
    11p11.2; chr11:46701030-46705912 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human ZNF408 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    21
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075040 Ensembl Gene Model | MGI Sequence Detail 6123 C57BL/6J ±  kb
transcript ENSMUST00000099714 Ensembl | MGI Sequence Detail 3469 Not Applicable  
polypeptide ENSMUSP00000097301 Ensembl | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR050717 C2H2-type Zinc-Finger Transcription Regulators
    IPR046341 SET domain superfamily
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory