Cd101 MGI Mouse Gene Detail - MGI:2685862

Symbol

Cd101
Name

CD101 antigen
Synonyms

Igsf2, LOC381460

Feature Type

protein coding gene
IDs

MGI:2685862
NCBI Gene: 630146
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr3:100900845-100936872 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 43.90 cM
Mapping Data

1 experiment

SNPs within 2kb

348 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685862	protein coding gene	Chr3:100899505-100936872 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027672	protein coding gene	Chr3:102135412-102176410 (-)
A/J	MGP_AJ_G0027631	protein coding gene	Chr3:98915020-98954212 (-)
AKR/J	MGP_AKRJ_G0027597	protein coding gene	Chr3:101345322-101384419 (-)
BALB/cJ	MGP_BALBcJ_G0027644	protein coding gene	Chr3:98675366-98711570 (-)
C3H/HeJ	MGP_C3HHeJ_G0027373	protein coding gene	Chr3:101637723-101674816 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028087	protein coding gene	Chr3:105885160-105923485 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025428	protein coding gene	Chr3:95112615-95152738 (-)
CAST/EiJ	MGP_CASTEiJ_G0026829	protein coding gene	Chr3:100741248-100778653 (-)
CBA/J	MGP_CBAJ_G0027348	protein coding gene	Chr3:109530530-109572841 (-)
DBA/2J	MGP_DBA2J_G0027491	protein coding gene	Chr3:98156009-98192472 (-)
FVB/NJ	MGP_FVBNJ_G0027459	protein coding gene	Chr3:96088586-96125627 (-)
LP/J	MGP_LPJ_G0027598	protein coding gene	Chr3:103497107-103534010 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027489	protein coding gene	Chr3:115752154-115791312 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028142	protein coding gene	Chr3:100832063-100870634 (-)
PWK/PhJ	MGP_PWKPhJ_G0026556	protein coding gene	Chr3:97912072-97949147 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026378	protein coding gene	Chr3:98925139-98963855 (-)
WSB/EiJ	MGP_WSBEiJ_G0026909	protein coding gene	Chr3:101393066-101429107 (-)

Human Ortholog

CD101, CD101 molecule

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CD101, CD101 molecule
Synonyms

EWI-101, IGSF2, V7
Links

HGNC:5949

NCBI Gene ID: 9398

neXtProt AC: NX_Q93033

UniProt: Q93033
Chr Location

1p13.1; chr1:117001750-117036552 (+) GRCh38

MGI Vertebrate Homology

Cd101 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CD101
Gene Tree

Cd101

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

2
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Cd101
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

47 strains or lines available

Mice homozygous for a knock-out allele exhibit reduced Gr-1+ cells.

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All GO Annotations

3
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

34
RefSeq

5
UniProt

2
CCDS

CCDS51019.1, CCDS51020.1

Ensembl

ENSMUSG00000086564 (Evidence)
NCBI Gene

630146

			Length	Strain/Species	Flank
genomic	ENSMUSG00000086564	Ensembl Gene Model \| MGI Sequence Detail	36028	C57BL/6J	± kb
transcript	ENSMUST00000147399	Ensembl \| MGI Sequence Detail	3299	Not Applicable
polypeptide	ENSMUSP00000116643	Ensembl \| MGI Sequence Detail	1033	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000001089 immunoglobulin superfamily member 2

(term hierarchy)
InterPro Domains

IPR013151 Immunoglobulin

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR003598 Immunoglobulin subtype 2

IPR051102 Immunoglobulin superfamily V-set and transmembrane domain-containing protein

IPR013106 Immunoglobulin V-set domain
GlyGen

A8E0Y8 2 sites

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All nucleic 2

cDNA 2

Microarray probesets 1

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MGI:2685580

Summaries

All 29

Diseases 1

Gene Ontology 3

Phenotypes 10
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Cd101:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34768	Chr3:100936859-100936874 (-)	5 bp
Tssr34767	Chr3:100936840-100936849 (-)	27 bp
Tssr34766	Chr3:100919994-100920003 (-)	16,873 bp
Tssr34765	Chr3:100919464-100919478 (-)	17,401 bp
Tssr34764	Chr3:100919446-100919457 (-)	17,420 bp
Tssr34763	Chr3:100919427-100919444 (-)	17,436 bp
Tssr34762	Chr3:100911126-100911145 (-)	25,736 bp
Tssr34761	Chr3:100911070-100911105 (-)	25,784 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24