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Mroh7 Gene Detail
Summary
  • Symbol
    Mroh7
  • Name
    maestro heat-like repeat family member 7
  • Synonyms
    Gm1027, Heatr8, LOC381538
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685873
    NCBI Gene: 381538
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106537614-106588122 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 49.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1599 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685873
 protein coding gene Chr4:106537614-106595059 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028525
 protein coding gene Chr4:107317806-107374513 (-)
A/J MGP_AJ_G0028488
 protein coding gene Chr4:103485591-103533518 (-)
AKR/J MGP_AKRJ_G0028435
 protein coding gene Chr4:105998930-106052661 (-)
BALB/cJ MGP_BALBcJ_G0028507
 protein coding gene Chr4:103673530-103723218 (-)
C3H/HeJ MGP_C3HHeJ_G0028221
 protein coding gene Chr4:106752691-106802366 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028947
 protein coding gene Chr4:111189695-111242798 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026238
 protein coding gene Chr4:98762449-98810091 (-)
CAST/EiJ MGP_CASTEiJ_G0027657
 protein coding gene Chr4:104552935-104609541 (-)
CBA/J MGP_CBAJ_G0028190
 protein coding gene Chr4:114777004-114837049 (-)
DBA/2J MGP_DBA2J_G0028338
 protein coding gene Chr4:103102541-103151970 (-)
FVB/NJ MGP_FVBNJ_G0028306
 protein coding gene Chr4:101959040-102010641 (-)
LP/J MGP_LPJ_G0028439
 protein coding gene Chr4:107517989-107572968 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028332
 protein coding gene Chr4:120101280-120154666 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028983
 protein coding gene Chr4:106247912-106300905 (-)
PWK/PhJ MGP_PWKPhJ_G0027383
 protein coding gene Chr4:101338819-101388933 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027207
 protein coding gene Chr4:103630070-103687234 (-)
WSB/EiJ MGP_WSBEiJ_G0027738
 protein coding gene Chr4:106422536-106475376 (-)



Homology
more
  • Human Ortholog
    MROH7, maestro heat like repeat family member 7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH7, maestro heat like repeat family member 7
  • Synonyms
    C1orf175, HEATR8
  • Links
    NCBI Gene ID: 374977
    neXtProt AC: NX_Q68CQ1
    UniProt: Q68CQ1

  • Chr Location
    1p32.3; chr1:54641754-54710266 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Male mice for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047502 Ensembl Gene Model | MGI Sequence Detail 50509 C57BL/6J ±  kb
    transcript ENSMUST00000106770 Ensembl | MGI Sequence Detail 4346 Not Applicable  
    polypeptide ENSMUSP00000102382 Ensembl | MGI Sequence Detail 1279 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 32
      Gene Ontology 2
      Phenotypes 14
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:348435 Suzuki A, et al., Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male mice. J Reprod Immunol. 2024;:104252
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory