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Foxr1 Gene Detail
Summary
  • Symbol
    Foxr1
  • Name
    forkhead box R1
  • Synonyms
    Foxn5, LOC382074
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685961
    NCBI Gene: 382074
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:44345531-44352165 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 24.84 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685961
protein coding gene Chr9:44345070-44352433 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034710
protein coding gene Chr9:42922696-42929363 (-)
A/J MGP_AJ_G0034691
protein coding gene Chr9:41726197-41732832 (-)
AKR/J MGP_AKRJ_G0034617
protein coding gene Chr9:42589070-42595704 (-)
BALB/cJ MGP_BALBcJ_G0034682
protein coding gene Chr9:41472336-41478971 (-)
C3H/HeJ MGP_C3HHeJ_G0034393
protein coding gene Chr9:43047413-43054048 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035203
protein coding gene Chr9:44194610-44201244 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032118
protein coding gene Chr9:41299394-41306055 (-)
CAST/EiJ MGP_CASTEiJ_G0033715
protein coding gene Chr9:42893872-42900541 (-)
CBA/J MGP_CBAJ_G0034365
protein coding gene Chr9:45807565-45814199 (-)
DBA/2J MGP_DBA2J_G0034524
protein coding gene Chr9:41627420-41634055 (-)
FVB/NJ MGP_FVBNJ_G0034465
protein coding gene Chr9:40880531-40887165 (-)
LP/J MGP_LPJ_G0034605
protein coding gene Chr9:43227382-43234049 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034509
protein coding gene Chr9:47646851-47653486 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035224
protein coding gene Chr9:42488324-42494958 (-)
PWK/PhJ MGP_PWKPhJ_G0033421
protein coding gene Chr9:41504384-41511480 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033255
protein coding gene Chr9:42811475-42819465 (-)
WSB/EiJ MGP_WSBEiJ_G0033828
protein coding gene Chr9:42530467-42537101 (-)



Homology
more
  • Human Ortholog
    FOXR1, forkhead box R1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FOXR1, forkhead box R1
  • Synonyms
    DLNB13, FOXN5
  • Links
    NCBI Gene ID: 283150
    neXtProt AC: NX_Q6PIV2
    UniProt: Q6PIV2

  • Chr Location
    11q23.3; chr11:118971712-118981287 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 382074 NCBI Gene Model | MGI Sequence Detail 6635 C57BL/6J ±  kb
    transcript NM_001033469 RefSeq | MGI Sequence Detail 1666 ZRU/MplStud  
    polypeptide Q3UTB7 UniProt | EBI | MGI Sequence Detail 268 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 5
      Primer pair 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory