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Snx22 Gene Detail
Summary
  • Symbol
    Snx22
  • Name
    sorting nexin 22
  • Synonyms
    LOC382083
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685966
    NCBI Gene: 382083
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65972458-65977001 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    190 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685966
 protein coding gene Chr9:65972456-65977041 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034971
 protein coding gene Chr9:65868008-65872563 (-)
A/J MGP_AJ_G0034951
 protein coding gene Chr9:63612423-63616978 (-)
AKR/J MGP_AKRJ_G0034881
 protein coding gene Chr9:65129427-65133982 (-)
BALB/cJ MGP_BALBcJ_G0034944
 protein coding gene Chr9:63327364-63331919 (-)
C3H/HeJ MGP_C3HHeJ_G0034654
 protein coding gene Chr9:65659660-65664215 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035463
 protein coding gene Chr9:67651642-67656197 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032374
 protein coding gene Chr9:63270736-63275301 (-)
CAST/EiJ MGP_CASTEiJ_G0033975
 protein coding gene Chr9:65854658-65859179 (-)
CBA/J MGP_CBAJ_G0034625
 protein coding gene Chr9:70006496-70011051 (-)
DBA/2J MGP_DBA2J_G0034784
 protein coding gene Chr9:63388023-63392579 (-)
FVB/NJ MGP_FVBNJ_G0034726
 protein coding gene Chr9:62730640-62735193 (-)
LP/J MGP_LPJ_G0034867
 protein coding gene Chr9:66117196-66121751 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034768
 protein coding gene Chr9:71254305-71258860 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035485
 protein coding gene Chr9:65238021-65242576 (-)
PWK/PhJ MGP_PWKPhJ_G0033679
 protein coding gene Chr9:63586609-63591162 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033513
 protein coding gene Chr9:65525128-65529664 (-)
WSB/EiJ MGP_WSBEiJ_G0034088
 protein coding gene Chr9:65136974-65141529 (-)



Homology
more
  • Human Ortholog
    SNX22, sorting nexin 22
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNX22, sorting nexin 22
  • Links
    NCBI Gene ID: 79856
    neXtProt AC: NX_Q96L94
    UniProt: Q96L94

  • Chr Location
    15q22.31; chr15:64151715-64157481 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    16
  • cDNA Data
    10
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039452 Ensembl Gene Model | MGI Sequence Detail 4544 C57BL/6J ±  kb
    transcript ENSMUST00000044711 Ensembl | MGI Sequence Detail 2543 Not Applicable  
    polypeptide ENSMUSP00000044389 Ensembl | MGI Sequence Detail 192 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR001683 Phox homology
      IPR036871 PX domain superfamily
      IPR052467 Sorting nexin PX domain-containing protein
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 14
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory