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Kif28 Gene Detail
Summary
  • Symbol
    Kif28
  • Name
    kinesin family member 28
  • Synonyms
    Gm1305, LOC383592
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686151
    NCBI Gene: 383592
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr1:179522862-179572836 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 83.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1698 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686151
 protein coding gene Chr1:179522602-179572836 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016862
 protein coding gene Chr1:186068331-186126933 (-)
A/J MGP_AJ_G0016841
 protein coding gene Chr1:178568352-178619159 (-)
AKR/J MGP_AKRJ_G0016807
 protein coding gene Chr1:183882556-183932917 (-)
BALB/cJ MGP_BALBcJ_G0016799
 protein coding gene Chr1:179198987-179250738 (-)
C3H/HeJ MGP_C3HHeJ_G0016624
 protein coding gene Chr1:184628112-184689923 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017262
 protein coding gene Chr1:192089486-192160543 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014970
 protein coding gene Chr1:169556377-169607194 (-)
CAST/EiJ MGP_CASTEiJ_G0016205
 protein coding gene Chr1:183936229-183992047 (-)
CBA/J MGP_CBAJ_G0016598
 protein coding gene Chr1:199255419-199315208 (-)
DBA/2J MGP_DBA2J_G0016704
 protein coding gene Chr1:177410909-177461978 (-)
FVB/NJ MGP_FVBNJ_G0016700
 protein coding gene Chr1:175492537-175545799 (-)
LP/J MGP_LPJ_G0016778
 protein coding gene Chr1:187343014-187402105 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016731
 protein coding gene Chr1:206383442-206458624 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017299
 protein coding gene Chr1:183620013-183677060 (-)
PWK/PhJ MGP_PWKPhJ_G0015993
 protein coding gene Chr1:176491624-176544335 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015769
 protein coding gene Chr1:182571712-182624134 (-)
WSB/EiJ MGP_WSBEiJ_G0016268
 protein coding gene Chr1:183844261-183899769 (-)



Homology
more
  • Human Ortholog
    KIF28P, kinesin family member 28, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF28P, kinesin family member 28, pseudogene
  • Synonyms
    KLP-6
  • Links
    NCBI Gene ID: 100130097
    UniProt: B7ZC32

  • Chr Location
    1q44; chr1:246771837-246839611 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
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  • All Sequences
    37
  • RefSeq
    3
  • UniProt
    5
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000087236 Ensembl Gene Model | MGI Sequence Detail 49975 C57BL/6J ±  kb
transcript ENSMUST00000221136 Ensembl | MGI Sequence Detail 3538 Not Applicable  
polypeptide ENSMUSP00000152770 Ensembl | MGI Sequence Detail 1034 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR000253 Forkhead-associated (FHA) domain
    IPR022140 Kinesin-like KIF1-type
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR036961 Kinesin motor domain superfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR008984 SMAD/FHA domain superfamily
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:5883133
References
more
  • Summaries
    All 22
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory