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Ptprh Gene Detail
Summary
  • Symbol
    Ptprh
  • Name
    protein tyrosine phosphatase receptor type H
  • Synonyms
    SAP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026877
    NCBI Gene: 545902
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:4551611-4607040 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1026 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026877
 protein coding gene Chr7:4551607-4607040 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031551
 protein coding gene Chr7:1469499-1519376 (-)
A/J MGP_AJ_G0031525
 protein coding gene Chr7:1468477-1534626 (-)
AKR/J MGP_AKRJ_G0031454
 protein coding gene Chr7:1546479-1598979 (-)
BALB/cJ MGP_BALBcJ_G0031533
 protein coding gene Chr7:1534160-1579270 (-)
C3H/HeJ MGP_C3HHeJ_G0031254
 protein coding gene Chr7:1511867-1572256 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031994
 protein coding gene Chr7:1507275-1519128 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029118
 protein coding gene Chr7:1241297-1252103 (-)
CAST/EiJ MGP_CASTEiJ_G0030618
 protein coding gene Chr7:1451732-1510749 (-)
CBA/J MGP_CBAJ_G0031212
 protein coding gene Chr7:1708125-1768325 (-)
DBA/2J MGP_DBA2J_G0031371
 protein coding gene Chr7:1435433-1445326 (-)
FVB/NJ MGP_FVBNJ_G0031323
 protein coding gene Chr7:1415202-1481027 (-)
LP/J MGP_LPJ_G0031456
 protein coding gene Chr7:1559897-1635632 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031362
 protein coding gene Chr7:1635479-1702944 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032024
 protein coding gene Chr7:1449641-1504399 (-)
PWK/PhJ MGP_PWKPhJ_G0030346
 protein coding gene Chr7:1622338-1632290 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030171
 protein coding gene Chr7:1511875-1561637 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PTPRH, protein tyrosine phosphatase receptor type H
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTPRH, protein tyrosine phosphatase receptor type H
  • Synonyms
    R-PTP-H, SAP1
  • Links
    NCBI Gene ID: 5794
    neXtProt AC: NX_Q9HD43
    UniProt: Q9HD43

  • Chr Location
    19q13.42; chr19:55181247-55209506 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    48 phenotype references
Mice homozygous for a null alllele exhibit normal intestinal epithelial cell morphology and physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    26
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035429 Ensembl Gene Model | MGI Sequence Detail 55430 C57BL/6J ±  kb
transcript ENSMUST00000206999 Ensembl | MGI Sequence Detail 3495 Not Applicable  
polypeptide ENSMUSP00000145543 Ensembl | MGI Sequence Detail 971 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 69
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 48
  • Earliest
    J:148234 Cao YA, et al., Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):221-6
  • Latest
    J:352591 Babey ME, et al., A maternal brain hormone that builds bone. Nature. 2024 Aug;632(8024):357-365
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory