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Ccdc87 Gene Detail
Summary
  • Symbol
    Ccdc87
  • Name
    coiled-coil domain containing 87
  • Synonyms
    4931419P11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026882
    NCBI Gene: 399599
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:4889394-4892556 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.11 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026882
 protein coding gene Chr19:4889394-4892556 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024676
 protein coding gene Chr19:1735969-1739131 (+)
A/J MGP_AJ_G0024642
 protein coding gene Chr19:1655697-1658859 (+)
AKR/J MGP_AKRJ_G0024615
 protein coding gene Chr19:1702972-1706134 (+)
BALB/cJ MGP_BALBcJ_G0024642
 protein coding gene Chr19:1651656-1654818 (+)
C3H/HeJ MGP_C3HHeJ_G0024410
 protein coding gene Chr19:1704851-1708013 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025089
 protein coding gene Chr19:1789649-1792811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022519
 protein coding gene Chr19:1588091-1591262 (+)
CAST/EiJ MGP_CASTEiJ_G0023882
 protein coding gene Chr19:1725430-1728592 (+)
CBA/J MGP_CBAJ_G0024381
 protein coding gene Chr19:1865413-1868575 (+)
DBA/2J MGP_DBA2J_G0024509
 protein coding gene Chr19:1623235-1626397 (+)
FVB/NJ MGP_FVBNJ_G0024476
 protein coding gene Chr19:1645332-1648494 (+)
LP/J MGP_LPJ_G0024595
 protein coding gene Chr19:1747788-1750950 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024506
 protein coding gene Chr19:1771955-1775117 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025137
 protein coding gene Chr19:1695005-1698167 (+)
PWK/PhJ MGP_PWKPhJ_G0023628
 protein coding gene Chr19:1672804-1675966 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023433
 protein coding gene Chr19:1683609-1686770 (+)
WSB/EiJ MGP_WSBEiJ_G0023944
 protein coding gene Chr19:1695055-1698211 (+)



Homology
more
  • Human Ortholog
    CCDC87, coiled-coil domain containing 87
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC87, coiled-coil domain containing 87
  • Links
    NCBI Gene ID: 55231
    neXtProt AC: NX_Q9NVE4
    UniProt: Q9NVE4

  • Chr Location
    11q13.2; chr11:66590176-66593063 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit male subfertility or infertility associated with severe sperm head defects, decreased initial sperm motility, impaired acrosome reaction, and loss of fertilizing capacity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 399599 NCBI Gene Model | MGI Sequence Detail 3163 C57BL/6J ±  kb
    transcript NM_207268 RefSeq | MGI Sequence Detail 3163 C57BL/6  
    polypeptide Q8CDL9 UniProt | EBI | MGI Sequence Detail 855 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 24
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory