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Plk5 Gene Detail
Summary
  • Symbol
    Plk5
  • Name
    polo like kinase 5
  • Synonyms
    6330514A18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3026984
    NCBI Gene: 216166
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80192293-80201323 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3026984
 protein coding gene Chr10:80192293-80201323 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017499
 protein coding gene Chr10:80959573-80968387 (+)
A/J MGP_AJ_G0017477
 protein coding gene Chr10:78124313-78133443 (+)
AKR/J MGP_AKRJ_G0017438
 protein coding gene Chr10:80264837-80274031 (+)
BALB/cJ MGP_BALBcJ_G0017439
 protein coding gene Chr10:78353372-78362739 (+)
C3H/HeJ MGP_C3HHeJ_G0017262
 protein coding gene Chr10:80355087-80364115 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017893
 protein coding gene Chr10:83762205-83770983 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015581
 protein coding gene Chr10:74343083-74351076 (+)
CAST/EiJ MGP_CASTEiJ_G0016829
 protein coding gene Chr10:80568672-80577002 (+)
CBA/J MGP_CBAJ_G0017234
 protein coding gene Chr10:86999490-87008560 (+)
DBA/2J MGP_DBA2J_G0017340
 protein coding gene Chr10:77341602-77350990 (+)
FVB/NJ MGP_FVBNJ_G0017334
 protein coding gene Chr10:76533829-76542258 (+)
LP/J MGP_LPJ_G0017411
 protein coding gene Chr10:81429249-81438263 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017360
 protein coding gene Chr10:88954056-88964296 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017934
 protein coding gene Chr10:80250212-80259312 (+)
PWK/PhJ MGP_PWKPhJ_G0016610
 protein coding gene Chr10:77212623-77224222 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016399
 protein coding gene Chr10:79219828-79227589 (+)
WSB/EiJ MGP_WSBEiJ_G0016889
 protein coding gene Chr10:80283063-80292139 (+)



Homology
more
  • Human Ortholog
    PLK5, polo like kinase 5 (inactive)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLK5, polo like kinase 5 (inactive)
  • Synonyms
    PLK-5, PLK5P, SgK384ps
  • Links
    NCBI Gene ID: 126520
    neXtProt AC: NX_Q496M5
    UniProt: Q496M5

  • Chr Location
    19p13.3; chr19:1508023-1536046 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    745
  • Tissues
    30
  • cDNA Data
    17
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216166 NCBI Gene Model | MGI Sequence Detail 9031 C57BL/6J ±  kb
transcript NM_001433556 RefSeq | MGI Sequence Detail 2107 C57BL/6  
polypeptide Q4FZD7 UniProt | EBI | MGI Sequence Detail 595 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory