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Clec4a1 Gene Detail
Summary
  • Symbol
    Clec4a1
  • Name
    C-type lectin domain family 4, member a1
  • Synonyms
    mDcir4
  • Feature Type
    protein coding gene
  • IDs
    MGI:3036291
    NCBI Gene: 269799
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:122898807-122911578 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 58.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    427 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3036291
 protein coding gene Chr6:122898807-122911578 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031236
 protein coding gene Chr6:126043001-126055827 (+)
A/J MGP_AJ_G0031205
 protein coding gene Chr6:121264775-121278149 (+)
AKR/J MGP_AKRJ_G0031135
 protein coding gene Chr6:124626174-124638940 (+)
BALB/cJ MGP_BALBcJ_G0031215
 protein coding gene Chr6:120976651-120993259 (+)
C3H/HeJ MGP_C3HHeJ_G0030934
 protein coding gene Chr6:124587049-124601050 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031674
 protein coding gene Chr6:129371478-129385872 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030323
 protein coding gene Chr6:124855312-124868376 (+)
CBA/J MGP_CBAJ_G0030897
 protein coding gene Chr6:134413990-134426757 (+)
DBA/2J MGP_DBA2J_G0031053
 protein coding gene Chr6:120196037-120208967 (+)
FVB/NJ MGP_FVBNJ_G0031006
 protein coding gene Chr6:119134464-119148229 (+)
LP/J MGP_LPJ_G0031134
 protein coding gene Chr6:126232504-126249533 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031041
 protein coding gene Chr6:138367064-138388515 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031704
 protein coding gene Chr6:124511902-124524673 (+)
PWK/PhJ MGP_PWKPhJ_G0030037
 protein coding gene Chr6:119036349-119049486 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029865
 protein coding gene Chr6:122655376-122668423 (+)
WSB/EiJ MGP_WSBEiJ_G0030405
 protein coding gene Chr6:124825092-124838850 (+)



Homology
more
  • Human Ortholog
    CLEC4A, C-type lectin domain family 4 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLEC4A, C-type lectin domain family 4 member A
  • Synonyms
    CD367, CLECSF6, DCIR, DDB27, HDCGC13P, hDCIR, LLIR
  • Links
    NCBI Gene ID: 50856
    neXtProt AC: NX_Q9UMR7
    UniProt: Q9UMR7

  • Chr Location
    12p13.31; chr12:8102907-8138607 (+)  GRCh38
  • Human Ortholog
    ZNF705A, zinc finger protein 705A
  • Links
    NCBI Gene ID: 440077
    neXtProt AC: NX_Q6ZN79
    UniProt: Q6ZN79

  • Chr Location
    12p13.31; chr12:8157015-8188537 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269799 NCBI Gene Model | MGI Sequence Detail 12772 C57BL/6J ±  kb
transcript NM_199311 RefSeq | MGI Sequence Detail 1592 C57BL/6  
polypeptide NP_955015 RefSeq | MGI Sequence Detail 245 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR033989 CD209-like, C-type lectin-like domain
    IPR016187 C-type lectin fold
    IPR001304 C-type lectin-like
    IPR016186 C-type lectin-like/link domain superfamily
    IPR051379 C-type Lectin Receptor Immune Modulators
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 16
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:93065 Flornes LM, et al., Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. Immunogenetics. 2004 Oct;56(7):506-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory