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Thada Gene Detail
Summary
  • Symbol
    Thada
  • Name
    thyroid adenoma associated
  • Feature Type
    protein coding gene
  • IDs
    MGI:3039623
    NCBI Gene: 240174
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:84497504-84773633 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 55.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3039623
 protein coding gene Chr17:84497484-84773674 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024078
 protein coding gene Chr17:87334015-87626893 (-)
A/J MGP_AJ_G0024037
 protein coding gene Chr17:84577504-84853110 (-)
AKR/J MGP_AKRJ_G0024006
 protein coding gene Chr17:85950103-86234965 (-)
BALB/cJ MGP_BALBcJ_G0024038
 protein coding gene Chr17:84428885-84702993 (-)
C3H/HeJ MGP_C3HHeJ_G0023803
 protein coding gene Chr17:86796239-87079569 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024483
 protein coding gene Chr17:90443674-90741452 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021922
 protein coding gene Chr17:79786134-80061479 (-)
CAST/EiJ MGP_CASTEiJ_G0023282
 protein coding gene Chr17:87568733-87868823 (-)
CBA/J MGP_CBAJ_G0023777
 protein coding gene Chr17:94174739-94479925 (-)
DBA/2J MGP_DBA2J_G0023905
 protein coding gene Chr17:83065361-83335437 (-)
FVB/NJ MGP_FVBNJ_G0023871
 protein coding gene Chr17:82541979-82814879 (-)
LP/J MGP_LPJ_G0023989
 protein coding gene Chr17:88091423-88387078 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023899
 protein coding gene Chr17:94285344-94574365 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024528
 protein coding gene Chr17:86438211-86718419 (-)
PWK/PhJ MGP_PWKPhJ_G0023027
 protein coding gene Chr17:82625027-82899158 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022838
 protein coding gene Chr17:83233487-83526285 (-)
WSB/EiJ MGP_WSBEiJ_G0023348
 protein coding gene Chr17:87300962-87588714 (-)



Homology
more
  • Human Ortholog
    THADA, THADA armadillo repeat containing
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THADA, THADA armadillo repeat containing
  • Synonyms
    ARMC13, GITA, Trm732
  • Links
    NCBI Gene ID: 63892
    neXtProt AC: NX_Q6YHU6
    UniProt: Q6YHU6

  • Chr Location
    2p21; chr2:43230851-43596038 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Homozygous null mice show normal development from birth to adulthood and normal fertility. Females show normal ovarian development, function, and ovulation and high-fat-high-sugar diet does not induce reproductive dysfunction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    11
  • cDNA Data
    53
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024251 Ensembl Gene Model | MGI Sequence Detail 276130 C57BL/6J ±  kb
transcript ENSMUST00000047524 Ensembl | MGI Sequence Detail 7784 Not Applicable  
polypeptide ENSMUSP00000041701 Ensembl | MGI Sequence Detail 1938 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 2
Other
Accession IDs
less
MGI:2146983
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory