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Zfp458 Gene Detail
Summary
  • Symbol
    Zfp458
  • Name
    zinc finger protein 458
  • Synonyms
    Rslcan-7
  • Feature Type
    protein coding gene
  • IDs
    MGI:3040691
    NCBI Gene: 238690
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:67402982-67426530 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 34.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    554 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3040691
 protein coding gene Chr13:67350853-67426530 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020704
 protein coding gene Chr13:67400916-67416768 (-)
A/J MGP_AJ_G0020656
 protein coding gene Chr13:64915588-64934187 (-)
AKR/J MGP_AKRJ_G0026054
 protein coding gene Chr2:89914560-89918474 (+)
BALB/cJ MGP_BALBcJ_G0020655
 protein coding gene Chr13:65417030-65432486 (-)
C3H/HeJ MGP_C3HHeJ_G0020450
 protein coding gene Chr13:66713568-66727672 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021090
 protein coding gene Chr13:69774917-69793601 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018662
 protein coding gene Chr13:62564172-62579691 (-)
CAST/EiJ MGP_CASTEiJ_G0019969
 protein coding gene Chr13:65960342-65974981 (-)
CBA/J MGP_CBAJ_G0020409
 protein coding gene Chr13:72241756-72260098 (-)
DBA/2J MGP_DBA2J_G0020535
 protein coding gene Chr13:64818037-64832964 (-)
FVB/NJ MGP_FVBNJ_G0020513
 protein coding gene Chr13:63838528-63852320 (-)
LP/J MGP_LPJ_G0020609
 protein coding gene Chr13:67641900-67655841 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020543
 protein coding gene Chr13:71070491-71086927 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021132
 protein coding gene Chr13:66355585-66360941 (-)
PWK/PhJ MGP_PWKPhJ_G0019720
 protein coding gene Chr13:63718945-63733480 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019549
 protein coding gene Chr13:63401725-63414339 (-)
WSB/EiJ MGP_WSBEiJ_G0020030
 protein coding gene Chr13:66826134-66841974 (-)



Homology
more
  • Human Ortholog
    ZNF43, zinc finger protein 43
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF43, zinc finger protein 43
  • Synonyms
    HTF6, KOX27, ZNF39L1
  • Links
    NCBI Gene ID: 7594
    neXtProt AC: NX_P17038
    UniProt: P17038

  • Chr Location
    19p12; chr19:21804946-21852125 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055480 Ensembl Gene Model | MGI Sequence Detail 23549 C57BL/6J ±  kb
transcript ENSMUST00000045969 Ensembl | MGI Sequence Detail 3488 Not Applicable  
polypeptide ENSMUSP00000047222 Ensembl | MGI Sequence Detail 752 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory