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Ifi211 Gene Detail
Summary
  • Symbol
    Ifi211
  • Name
    interferon activated gene 211
  • Synonyms
    Ifi205b, Mnda
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041120
    NCBI Gene: 381308
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173723911-173740612 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041120
protein coding gene Chr1:173723907-173740650 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016818
protein coding gene Chr1:180010762-180068815 (-)
A/J MGP_AJ_G0016794
protein coding gene Chr1:172463739-172473214 (-)
AKR/J MGP_AKRJ_G0016762
protein coding gene Chr1:177923310-177985185 (-)
BALB/cJ MGP_BALBcJ_G0016756
protein coding gene Chr1:173265281-173284867 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014925
protein coding gene Chr1:164223594-164237151 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0016552
protein coding gene Chr1:192813109-192834675 (-)
DBA/2J MGP_DBA2J_G0016658
protein coding gene Chr1:171700803-171715007 (-)
FVB/NJ MGP_FVBNJ_G0016655
protein coding gene Chr1:169772740-169792755 (-)
LP/J MGP_LPJ_G0016735
protein coding gene Chr1:181149745-181163142 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016687
protein coding gene Chr1:199957095-199985829 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017251
protein coding gene Chr1:177657278-177682137 (-)
PWK/PhJ MGP_PWKPhJ_G0015944
protein coding gene Chr1:170565590-170580488 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0016223
protein coding gene Chr1:177870762-177945002 (-)



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38

  • Human Ortholog
    MNDA, myeloid cell nuclear differentiation antigen
  • Synonyms
    PYHIN3
  • Links
    NCBI Gene ID: 4332
    neXtProt AC: NX_P41218
    UniProt: P41218

  • Chr Location
    1q23.1; chr1:158831351-158849506 (+)  GRCh38

  • Human Ortholog
    PYHIN1, pyrin and HIN domain family member 1
  • Synonyms
    IFIX
  • Links
    NCBI Gene ID: 149628
    neXtProt AC: NX_Q6K0P9
    UniProt: Q6K0P9

  • Chr Location
    1q23.1; chr1:158930796-158990870 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026536 Ensembl Gene Model | MGI Sequence Detail 16702 C57BL/6J ±  kb
transcript ENSMUST00000009340 Ensembl | MGI Sequence Detail 1785 Not Applicable  
polypeptide ENSMUSP00000009340 Ensembl | MGI Sequence Detail 425 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    Genomic 1
    cDNA 32
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:8394 Samanta H, et al., Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene. J Biol Chem. 1986 Sep 5;261(25):11849-58
  • Latest
    J:329937 Maltbaek JH, et al., ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP. Immunity. 2022 Oct 11;55(10):1799-1812.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory