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Dipk1c Gene Detail
Summary
  • Symbol
    Dipk1c
  • Name
    divergent protein kinase domain 1C
  • Synonyms
    B230399E16Rik, Fam69c
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041188
    NCBI Gene: 240479
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:84737361-84758561 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 57.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    826 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041188
 protein coding gene Chr18:84737133-84762820 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024609
 protein coding gene Chr18:85881995-85902062 (+)
A/J MGP_AJ_G0024576
 protein coding gene Chr18:82111601-82133604 (+)
AKR/J MGP_AKRJ_G0024547
 protein coding gene Chr18:84559177-84580584 (+)
BALB/cJ MGP_BALBcJ_G0024574
 protein coding gene Chr18:82303351-82325133 (+)
C3H/HeJ MGP_C3HHeJ_G0024343
 protein coding gene Chr18:84660311-84679782 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025021
 protein coding gene Chr18:88019005-88039991 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022452
 protein coding gene Chr18:80803146-80823619 (+)
CAST/EiJ MGP_CASTEiJ_G0023816
 protein coding gene Chr18:85032645-85059639 (+)
CBA/J MGP_CBAJ_G0024313
 protein coding gene Chr18:91191498-91217364 (+)
DBA/2J MGP_DBA2J_G0024442
 protein coding gene Chr18:81631904-81651186 (+)
FVB/NJ MGP_FVBNJ_G0024409
 protein coding gene Chr18:80968302-80988787 (+)
LP/J MGP_LPJ_G0024527
 protein coding gene Chr18:85684343-85706469 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024439
 protein coding gene Chr18:92431892-92465175 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025070
 protein coding gene Chr18:84772910-84795115 (+)
PWK/PhJ MGP_PWKPhJ_G0023561
 protein coding gene Chr18:82028491-82055004 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023367
 protein coding gene Chr18:84800538-84820476 (+)
WSB/EiJ MGP_WSBEiJ_G0023878
 protein coding gene Chr18:84725993-84748462 (+)



Homology
more
  • Human Ortholog
    DIPK1C, divergent protein kinase domain 1C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIPK1C, divergent protein kinase domain 1C
  • Synonyms
    C18orf51, FAM69C, FNCAD
  • Links
    NCBI Gene ID: 125704
    neXtProt AC: NX_Q0P6D2
    UniProt: Q0P6D2

  • Chr Location
    18q22.3; chr18:74434775-74464648 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice exhibit impairments in synaptic plasticity, dendritic spine density, and memory, and show stress-induced neuronal death
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    794
  • Tissues
    14
  • cDNA Data
    6
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047992 Ensembl Gene Model | MGI Sequence Detail 21201 C57BL/6J ±  kb
transcript ENSMUST00000161429 Ensembl | MGI Sequence Detail 1387 Not Applicable  
polypeptide ENSMUSP00000124603 Ensembl | MGI Sequence Detail 410 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 1
Other
Accession IDs
less
MGI:6276591
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory