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Serpina7 Gene Detail
Summary
  • Symbol
    Serpina7
  • Name
    serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
  • Synonyms
    C730040N12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041197
    NCBI Gene: 331535
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:137980006-137985985 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 61.23 cM, cytoband F1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    200 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041197
 protein coding gene ChrX:137979998-137985985 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036118
 protein coding gene ChrX:136559119-136565098 (-)
A/J MGP_AJ_G0036097
 protein coding gene ChrX:135942076-135948055 (-)
AKR/J MGP_AKRJ_G0036021
 protein coding gene ChrX:140326468-140332447 (-)
BALB/cJ MGP_BALBcJ_G0036086
 protein coding gene ChrX:134301441-134307420 (-)
C3H/HeJ MGP_C3HHeJ_G0035795
 protein coding gene ChrX:136595604-136601583 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036611
 protein coding gene ChrX:140591276-140597255 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033436
 protein coding gene ChrX:127744736-127750748 (-)
CAST/EiJ MGP_CASTEiJ_G0035086
 protein coding gene ChrX:117396161-117402148 (-)
CBA/J MGP_CBAJ_G0035772
 protein coding gene ChrX:144856329-144862308 (-)
DBA/2J MGP_DBA2J_G0035929
 protein coding gene ChrX:135154609-135160588 (-)
FVB/NJ MGP_FVBNJ_G0035863
 protein coding gene ChrX:134379862-134385841 (-)
LP/J MGP_LPJ_G0036021
 protein coding gene ChrX:137528187-137534166 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035900
 protein coding gene ChrX:152387936-152395496 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036647
 protein coding gene ChrX:135899571-135905550 (-)
PWK/PhJ MGP_PWKPhJ_G0034779
 protein coding gene ChrX:114343734-114350392 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034606
 protein coding gene ChrX:117941992-117948005 (-)
WSB/EiJ MGP_WSBEiJ_G0035221
 protein coding gene ChrX:134199360-134205339 (-)



Homology
more
  • Human Ortholog
    SERPINA7, serpin family A member 7
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINA7, serpin family A member 7
  • Synonyms
    TBG, TBGQTL
  • Links
    NCBI Gene ID: 6906
    neXtProt AC: NX_P05543
    UniProt: P05543

  • Chr Location
    Xq22.3; chrX:106032435-106038727 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    2
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031271 Ensembl Gene Model | MGI Sequence Detail 5980 C57BL/6J ±  kb
transcript ENSMUST00000033626 Ensembl | MGI Sequence Detail 2330 Not Applicable  
polypeptide ENSMUSP00000033626 Ensembl | MGI Sequence Detail 426 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory