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Apol10b Gene Detail
Summary
  • Symbol
    Apol10b
  • Name
    apolipoprotein L 10B
  • Synonyms
    9130218O11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3043522
    NCBI Gene: 328561
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:77468019-77480325 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    538 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3043522
 protein coding gene Chr15:77468019-77482796 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022027
 protein coding gene Chr15:77729206-77740223 (-)
A/J MGP_AJ_G0021989
 protein coding gene Chr15:75016567-75029660 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0021993
 protein coding gene Chr15:74996018-75007947 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0022434
 protein coding gene Chr15:80721488-80743812 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019962
 protein coding gene Chr15:71532305-71545133 (-)
CAST/EiJ MGP_CASTEiJ_G0021288
 protein coding gene Chr15:77878676-77891115 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0021927
 protein coding gene Chr15:77822293-77833165 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0022452
 protein coding gene Chr15:77165209-77179493 (-)
PWK/PhJ MGP_PWKPhJ_G0021027
 protein coding gene Chr15:74498909-74508726 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020865
 protein coding gene Chr15:76978391-76986632 (-)
WSB/EiJ MGP_WSBEiJ_G0021335
 protein coding gene Chr15:77329972-77342984 (-)



Homology
more
  • Human Ortholog
    APOL1, apolipoprotein L1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APOL1, apolipoprotein L1
  • Synonyms
    APO-L, APOL, APOL-I, FSGS4
  • Links
    NCBI Gene ID: 8542
    neXtProt AC: NX_O14791
    UniProt: O14791

  • Chr Location
    22q12.3; chr22:36253071-36267530 (+)  GRCh38
  • Human Ortholog
    APOL2, apolipoprotein L2
  • Synonyms
    APOL3, APOL-II
  • Links
    NCBI Gene ID: 23780
    neXtProt AC: NX_Q9BQE5
    UniProt: Q9BQE5

  • Chr Location
    22q12.3; chr22:36226209-36239954 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human APOL2,APOL4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000050014 Ensembl Gene Model | MGI Sequence Detail 12307 C57BL/6J ±  kb
    transcript ENSMUST00000089465 Ensembl | MGI Sequence Detail 2325 Not Applicable  
    polypeptide ENSMUSP00000086890 Ensembl | MGI Sequence Detail 334 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR008405 Apolipoprotein L
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 1
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 2
      Phenotypes 27
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory