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Kctd19 Gene Detail
Summary
  • Symbol
    Kctd19
  • Name
    potassium channel tetramerisation domain containing 19
  • Synonyms
    4922504H04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045294
    NCBI Gene: 279499
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106109439-106140134 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    732 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045294
 protein coding gene Chr8:106109433-106140134 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034044
 protein coding gene Chr8:107658201-107692534 (-)
A/J MGP_AJ_G0034025
 protein coding gene Chr8:103361332-103392224 (-)
AKR/J MGP_AKRJ_G0033951
 protein coding gene Chr8:106349359-106382308 (-)
BALB/cJ MGP_BALBcJ_G0034018
 protein coding gene Chr8:103539497-103571162 (-)
C3H/HeJ MGP_C3HHeJ_G0033730
 protein coding gene Chr8:107099110-107129619 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034538
 protein coding gene Chr8:111602047-111636426 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031480
 protein coding gene Chr8:96510037-96540078 (-)
CAST/EiJ MGP_CASTEiJ_G0033056
 protein coding gene Chr8:106595850-106627411 (-)
CBA/J MGP_CBAJ_G0033703
 protein coding gene Chr8:115216665-115257927 (-)
DBA/2J MGP_DBA2J_G0033858
 protein coding gene Chr8:102707338-102737916 (-)
FVB/NJ MGP_FVBNJ_G0033804
 protein coding gene Chr8:101631207-101661047 (-)
LP/J MGP_LPJ_G0033949
 protein coding gene Chr8:107866906-107901541 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033847
 protein coding gene Chr8:118416444-118450953 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034556
 protein coding gene Chr8:106324027-106356694 (-)
PWK/PhJ MGP_PWKPhJ_G0032757
 protein coding gene Chr8:102094571-102125505 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032598
 protein coding gene Chr8:104996460-105028243 (-)
WSB/EiJ MGP_WSBEiJ_G0033172
 protein coding gene Chr8:106977247-107009067 (-)



Homology
more
  • Human Ortholog
    KCTD19, potassium channel tetramerization domain containing 19
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCTD19, potassium channel tetramerization domain containing 19
  • Links
    NCBI Gene ID: 146212
    neXtProt AC: NX_Q17RG1
    UniProt: Q17RG1

  • Chr Location
    16q22.1; chr16:67289428-67326760 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 5 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are infertile, with delayed progression from early to mid/late pachynema and no mature spermatozoa in the cauda epididymis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    754
  • Tissues
    20
  • cDNA Data
    9
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051648 Ensembl Gene Model | MGI Sequence Detail 30696 C57BL/6J ±  kb
    transcript ENSMUST00000063071 Ensembl | MGI Sequence Detail 3048 Not Applicable  
    polypeptide ENSMUSP00000050687 Ensembl | MGI Sequence Detail 950 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 9
      Primer pair 2

      Microarray probesets 1
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory