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Slfnl1 Gene Detail
Summary
  • Symbol
    Slfnl1
  • Name
    schlafen like 1
  • Synonyms
    4933406A14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045330
    NCBI Gene: 194219
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120389446-120393858 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045330
 protein coding gene Chr4:120389428-120393858 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028709
 protein coding gene Chr4:121792018-121796448 (+)
A/J MGP_AJ_G0028669
 protein coding gene Chr4:116998297-117002727 (+)
AKR/J MGP_AKRJ_G0028622
 protein coding gene Chr4:119558392-119562822 (+)
BALB/cJ MGP_BALBcJ_G0028692
 protein coding gene Chr4:117605809-117610239 (+)
C3H/HeJ MGP_C3HHeJ_G0028407
 protein coding gene Chr4:121095577-121100007 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029133
 protein coding gene Chr4:126385231-126389661 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026410
 protein coding gene Chr4:111069739-111074171 (+)
CAST/EiJ MGP_CASTEiJ_G0027838
 protein coding gene Chr4:118461273-118465676 (+)
CBA/J MGP_CBAJ_G0028374
 protein coding gene Chr4:129816152-129820582 (+)
DBA/2J MGP_DBA2J_G0028521
 protein coding gene Chr4:117578409-117582839 (+)
FVB/NJ MGP_FVBNJ_G0028487
 protein coding gene Chr4:116106365-116110795 (+)
LP/J MGP_LPJ_G0028621
 protein coding gene Chr4:121917442-121921872 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028515
 protein coding gene Chr4:134653765-134658195 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029170
 protein coding gene Chr4:120629846-120634276 (+)
PWK/PhJ MGP_PWKPhJ_G0027561
 protein coding gene Chr4:114523045-114527445 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027387
 protein coding gene Chr4:117064727-117069118 (+)
WSB/EiJ MGP_WSBEiJ_G0027918
 protein coding gene Chr4:120639282-120643712 (+)



Homology
more
  • Human Ortholog
    SLFNL1, schlafen like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLFNL1, schlafen like 1
  • Links
    NCBI Gene ID: 200172
    neXtProt AC: NX_Q499Z3
    UniProt: Q499Z3

  • Chr Location
    1p34.2; chr1:41015589-41023237 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Male mice exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    10
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 194219 NCBI Gene Model | MGI Sequence Detail 4413 C57BL/6J ±  kb
    transcript NM_177570 RefSeq | MGI Sequence Detail 1744 C57BL/6  
    polypeptide Q8BHW9 UniProt | EBI | MGI Sequence Detail 410 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 11
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:296968 Park S, et al., CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity. Biol Reprod. 2020 Aug 4;103(2):195-204
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory