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Arhgef37 Gene Detail
Summary
  • Symbol
    Arhgef37
  • Name
    Rho guanine nucleotide exchange factor 37
  • Synonyms
    4933429F08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045339
    NCBI Gene: 328967
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:61624728-61669665 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 34.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1392 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045339
 protein coding gene Chr18:61624728-61669994 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024480
 protein coding gene Chr18:61381772-61427702 (-)
A/J MGP_AJ_G0024447
 protein coding gene Chr18:58745444-58793445 (-)
AKR/J MGP_AKRJ_G0024417
 protein coding gene Chr18:60362758-60399596 (-)
BALB/cJ MGP_BALBcJ_G0024446
 protein coding gene Chr18:58873661-58917438 (-)
C3H/HeJ MGP_C3HHeJ_G0024214
 protein coding gene Chr18:60598297-60645088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024893
 protein coding gene Chr18:63046161-63093866 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022324
 protein coding gene Chr18:58287339-58331663 (-)
CAST/EiJ MGP_CASTEiJ_G0023687
 protein coding gene Chr18:60473327-60517697 (-)
CBA/J MGP_CBAJ_G0024184
 protein coding gene Chr18:65070267-65126874 (-)
DBA/2J MGP_DBA2J_G0024314
 protein coding gene Chr18:58412010-58455401 (-)
FVB/NJ MGP_FVBNJ_G0024280
 protein coding gene Chr18:57824620-57866661 (-)
LP/J MGP_LPJ_G0024397
 protein coding gene Chr18:61234904-61281606 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024309
 protein coding gene Chr18:66674800-66721492 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024940
 protein coding gene Chr18:60564476-60615597 (-)
PWK/PhJ MGP_PWKPhJ_G0023430
 protein coding gene Chr18:58646609-58691906 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023236
 protein coding gene Chr18:60799851-60846936 (-)
WSB/EiJ MGP_WSBEiJ_G0023751
 protein coding gene Chr18:60423513-60469510 (-)



Homology
more
  • Human Ortholog
    ARHGEF37, Rho guanine nucleotide exchange factor 37
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGEF37, Rho guanine nucleotide exchange factor 37
  • Links
    NCBI Gene ID: 389337
    neXtProt AC: NX_A1IGU5
    UniProt: A1IGU5

  • Chr Location
    5q32; chr5:149551625-149634968 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045094 Ensembl Gene Model | MGI Sequence Detail 44938 C57BL/6J ±  kb
transcript ENSMUST00000171629 Ensembl | MGI Sequence Detail 5429 Not Applicable  
polypeptide ENSMUSP00000130560 Ensembl | MGI Sequence Detail 676 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory