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Igfn1 Gene Detail
Summary
  • Symbol
    Igfn1
  • Name
    immunoglobulin-like and fibronectin type III domain containing 1
  • Synonyms
    9830123M21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045352
    NCBI Gene: 226438
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135881316-135934080 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1822 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045352
 protein coding gene Chr1:135880943-135968663 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016532
 protein coding gene Chr1:139743101-139800247 (-)
A/J MGP_AJ_G0016515
 protein coding gene Chr1:134458221-134511459 (-)
AKR/J MGP_AKRJ_G0016480
 protein coding gene Chr1:138465145-138517577 (-)
BALB/cJ MGP_BALBcJ_G0016475
 protein coding gene Chr1:134783568-134835957 (-)
C3H/HeJ MGP_C3HHeJ_G0016301
 protein coding gene Chr1:138555017-138607471 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016936
 protein coding gene Chr1:144774739-144828266 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014647
 protein coding gene Chr1:127563886-127616587 (-)
CAST/EiJ MGP_CASTEiJ_G0015881
 protein coding gene Chr1:137620954-137698514 (-)
CBA/J MGP_CBAJ_G0016274
 protein coding gene Chr1:149785006-149844048 (-)
DBA/2J MGP_DBA2J_G0016380
 protein coding gene Chr1:133454540-133508180 (-)
FVB/NJ MGP_FVBNJ_G0016379
 protein coding gene Chr1:132101718-132154417 (-)
LP/J MGP_LPJ_G0016451
 protein coding gene Chr1:140976003-141030564 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016404
 protein coding gene Chr1:155437055-155491667 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016972
 protein coding gene Chr1:138225003-138277422 (-)
PWK/PhJ MGP_PWKPhJ_G0015667
 protein coding gene Chr1:132476066-132549326 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015454
 protein coding gene Chr1:137185943-137261994 (-)
WSB/EiJ MGP_WSBEiJ_G0015944
 protein coding gene Chr1:138270415-138323612 (-)



Homology
more
  • Human Ortholog
    IGFN1, immunoglobulin like and fibronectin type III domain containing 1
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGFN1, immunoglobulin like and fibronectin type III domain containing 1
  • Synonyms
    EEF1A2BP1
  • Links
    NCBI Gene ID: 91156
    neXtProt AC: NX_Q86VF2
    UniProt: Q86VF2

  • Chr Location
    1q32.1; chr1:201190824-201228952 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Homozygous mutant mice are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    5
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051985 Ensembl Gene Model | MGI Sequence Detail 52765 C57BL/6J ±  kb
transcript ENSMUST00000166193 Ensembl | MGI Sequence Detail 8989 Not Applicable  
polypeptide ENSMUSP00000129680 Ensembl | MGI Sequence Detail 2849 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory