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Pdzrn4 Gene Detail
Summary
  • Symbol
    Pdzrn4
  • Name
    PDZ domain containing RING finger 4
  • Synonyms
    1110017D07Rik, LNX4, mKIAA3027, SAMCAP3L
  • Feature Type
    protein coding gene
  • IDs
    MGI:3056996
    NCBI Gene: 239618
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:92294762-92669700 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 46.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    10633 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3056996
 protein coding gene Chr15:92294691-92669700 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022252
 protein coding gene Chr15:93765854-94150655 (+)
A/J MGP_AJ_G0022211
 protein coding gene Chr15:90155557-90516593 (+)
AKR/J MGP_AKRJ_G0022186
 protein coding gene Chr15:92813483-93188079 (+)
BALB/cJ MGP_BALBcJ_G0022217
 protein coding gene Chr15:90260962-90639088 (+)
C3H/HeJ MGP_C3HHeJ_G0021987
 protein coding gene Chr15:92828164-93214694 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022662
 protein coding gene Chr15:97177094-97589103 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020188
 protein coding gene Chr15:86246719-86603011 (+)
CAST/EiJ MGP_CASTEiJ_G0021509
 protein coding gene Chr15:93650006-94030538 (+)
CBA/J MGP_CBAJ_G0021954
 protein coding gene Chr15:100510280-100915428 (+)
DBA/2J MGP_DBA2J_G0022081
 protein coding gene Chr15:89589022-89955531 (+)
FVB/NJ MGP_FVBNJ_G0022060
 protein coding gene Chr15:88612296-88978205 (+)
LP/J MGP_LPJ_G0022152
 protein coding gene Chr15:93935499-94289641 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022080
 protein coding gene Chr15:104847885-105249852 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022677
 protein coding gene Chr15:92923700-93301126 (+)
PWK/PhJ MGP_PWKPhJ_G0021250
 protein coding gene Chr15:89639515-90001495 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021084
 protein coding gene Chr15:92666702-93053124 (+)
WSB/EiJ MGP_WSBEiJ_G0021558
 protein coding gene Chr15:93394249-93776596 (+)



Homology
more
  • Human Ortholog
    PDZRN4, PDZ domain containing ring finger 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDZRN4, PDZ domain containing ring finger 4
  • Synonyms
    LNX4, SAMCAP3L
  • Links
    NCBI Gene ID: 29951
    neXtProt AC: NX_Q6ZMN7
    UniProt: Q6ZMN7

  • Chr Location
    12q12; chr12:41188320-41574745 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Pdzrn4
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    41 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    795
  • Tissues
    20
  • cDNA Data
    8
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036218 Ensembl Gene Model | MGI Sequence Detail 374939 C57BL/6J ±  kb
transcript ENSMUST00000169942 Ensembl | MGI Sequence Detail 3102 Not Applicable  
polypeptide ENSMUSP00000133159 Ensembl | MGI Sequence Detail 1014 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR051971 E3 ubiquitin-protein ligase PDZ domain-containing protein
    IPR001478 PDZ domain
    IPR036034 PDZ superfamily
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920967
References
more
  • Summaries
    All 45
    Developmental Gene Expression 3
    Diseases 1
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory