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Snord115 Complex/Cluster/Region Detail
Summary
  • Symbol
    Snord115
  • Name
    small nucleolar RNA, C/D Box 115 cluster
  • Synonyms
    MBII-52
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:3510326
    NCBI Gene: 493919
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 7, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygous mice carrying a paternally inherited deletion of the complex show normal energy balance, eating behavior, emotional responses and sociability, but an increase in latency to feed in the novelty-suppressed feeding test and increased brown adipose tissue weight when fed a high-fat diet.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    24
  • Tissues
    6
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Other Mouse Links
      GEO
    Sequences &
    Gene Models
    less
    • All Sequences
      1
    Representative SequencesLengthStrain/SpeciesFlank
    transcript AF357427 GenBank | ENA | DDBJ | MGI Sequence Detail 66 Not Specified  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 1
      Other 1

      Microarray probesets 16
    References
    more
    • Summaries
      All 15
      Developmental Gene Expression 6
      Phenotypes 1
    • Earliest
      J:66477 Cavaille J, et al., From the cover: identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14311-6
    • Latest
      J:305741 Hebras J, et al., Reassessment of the involvement of Snord115 in the serotonin 2c receptor pathway in a genetically relevant mouse model. Elife. 2020 Oct 5;9:e60862
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory