Dp(11Cops3-Rnf112)1Jrl Cytogenetic Marker Detail

Summary

• Symbol
  Dp(11Cops3-Rnf112)1Jrl
• Name
  duplication, Chr 11, James R Lupski 1
• Synonyms
  Dp(11)17, Dp(11Cops3-Zfp179)1Jrl, dup(11)(Csn3-Zfp179)

• Feature Type
  chromosomal duplication
• IDs
  MGI:3577248

Location &
Maps

• Sequence Map
  Chr11:59708621-61344957 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, Syntenic

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotypes from 1 allele in 1 genetic background
  15 phenotypes from multigenic genotypes
  8 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 9

  Diseases 1

  Phenotypes 8
• Earliest
  J:83302 Walz K, et al., Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol Cell Biol. 2003 May;23(10):3646-55
• Latest
  J:185284 Lacaria M, et al., Enriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits. Hum Mol Genet. 2012 Jul 15;21(14):3083-96