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Hs3st6 Gene Detail
Summary
  • Symbol
    Hs3st6
  • Name
    heparan sulfate (glucosamine) 3-O-sulfotransferase 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:3580487
    NCBI Gene: 328779
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:24971962-24977658 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3580487
 protein coding gene Chr17:24971565-24977664 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023322
 protein coding gene Chr17:23775567-23781237 (+)
A/J MGP_AJ_G0023282
 protein coding gene Chr17:23119195-23125003 (+)
AKR/J MGP_AKRJ_G0023249
 protein coding gene Chr17:23209602-23215260 (+)
BALB/cJ MGP_BALBcJ_G0023287
 protein coding gene Chr17:23320356-23326036 (+)
C3H/HeJ MGP_C3HHeJ_G0023047
 protein coding gene Chr17:23560319-23566004 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023730
 protein coding gene Chr17:24829008-24834648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021205
 protein coding gene Chr17:20585034-20590635 (+)
CAST/EiJ MGP_CASTEiJ_G0022549
 protein coding gene Chr17:23417833-23426699 (+)
CBA/J MGP_CBAJ_G0023023
 protein coding gene Chr17:25680574-25686249 (+)
DBA/2J MGP_DBA2J_G0023152
 protein coding gene Chr17:22711158-22717049 (+)
FVB/NJ MGP_FVBNJ_G0023122
 protein coding gene Chr17:22429922-22435586 (+)
LP/J MGP_LPJ_G0023229
 protein coding gene Chr17:24083550-24089218 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023141
 protein coding gene Chr17:25369839-25377570 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023768
 protein coding gene Chr17:23483599-23489418 (+)
PWK/PhJ MGP_PWKPhJ_G0022298
 protein coding gene Chr17:21458438-21464153 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022113
 protein coding gene Chr17:21521749-21527350 (+)
WSB/EiJ MGP_WSBEiJ_G0022612
 protein coding gene Chr17:23558338-23565326 (+)



Homology
more
  • Human Ortholog
    HS3ST6, heparan sulfate-glucosamine 3-sulfotransferase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HS3ST6, heparan sulfate-glucosamine 3-sulfotransferase 6
  • Synonyms
    3-OST-6, 3OST6, HAE8, HS3ST5
  • Links
    NCBI Gene ID: 64711
    neXtProt AC: NX_Q96QI5
    UniProt: Q96QI5

  • Chr Location
    16p13.3; chr16:1911475-1920940 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human HS3ST6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    807
  • Tissues
    100
  • cDNA Data
    5
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039628 Ensembl Gene Model | MGI Sequence Detail 5697 C57BL/6J ±  kb
transcript ENSMUST00000044922 Ensembl | MGI Sequence Detail 1220 Not Applicable  
polypeptide ENSMUSP00000040919 Ensembl | MGI Sequence Detail 342 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 5
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 7
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:353621 Patel VN, et al., Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory