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Wfdc13 Gene Detail
Summary
  • Symbol
    Wfdc13
  • Name
    WAP four-disulfide core domain 13
  • Feature Type
    protein coding gene
  • IDs
    MGI:3582777
    NCBI Gene: 408190
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164527027-164529626 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    249 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3582777
 protein coding gene Chr2:164527027-164529626 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026866
 protein coding gene Chr2:170169182-170172387 (+)
A/J MGP_AJ_G0026833
 protein coding gene Chr2:163220808-163223420 (+)
AKR/J MGP_AKRJ_G0026804
 protein coding gene Chr2:168069762-168072376 (+)
BALB/cJ MGP_BALBcJ_G0026842
 protein coding gene Chr2:163580211-163582823 (+)
C3H/HeJ MGP_C3HHeJ_G0026584
 protein coding gene Chr2:168432073-168434738 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027289
 protein coding gene Chr2:175102250-175104849 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024660
 protein coding gene Chr2:156633033-156635815 (+)
CAST/EiJ MGP_CASTEiJ_G0026042
 protein coding gene Chr2:168848761-168851549 (+)
CBA/J MGP_CBAJ_G0026561
 protein coding gene Chr2:181455425-181458037 (+)
DBA/2J MGP_DBA2J_G0026699
 protein coding gene Chr2:162388124-162390761 (+)
FVB/NJ MGP_FVBNJ_G0026665
 protein coding gene Chr2:160808416-160811037 (+)
LP/J MGP_LPJ_G0026801
 protein coding gene Chr2:170237279-170240446 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026684
 protein coding gene Chr2:185014654-185017266 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027346
 protein coding gene Chr2:167974993-167977620 (+)
PWK/PhJ MGP_PWKPhJ_G0025779
 protein coding gene Chr2:161986868-161990136 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025580
 protein coding gene Chr2:166880068-166882872 (+)
WSB/EiJ MGP_WSBEiJ_G0026115
 protein coding gene Chr2:168856883-168859493 (+)



Homology
more
  • Human Ortholog
    WFDC13, WAP four-disulfide core domain 13
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WFDC13, WAP four-disulfide core domain 13
  • Synonyms
    C20orf138, dJ601O1.3, WAP13
  • Links
    NCBI Gene ID: 164237
    neXtProt AC: NX_Q8IUB5
    UniProt: Q8IUB5

  • Chr Location
    20q13.12
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 408190 NCBI Gene Model | MGI Sequence Detail 2600 C57BL/6J ±  kb
transcript NM_001012704 RefSeq | MGI Sequence Detail 1074 C57BL/6  
polypeptide Q5DQQ6 UniProt | EBI | MGI Sequence Detail 81 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:99265 Clauss A, et al., The evolution of a genetic locus encoding small serine proteinase inhibitors. Biochem Biophys Res Commun. 2005 Jul 29;333(2):383-9
  • Latest
    J:300068 Andrade AD, et al., Lipopolysaccharide-induced epididymitis modifies the transcriptional profile of Wfdc genes in mice. Biol Reprod. 2021 Jan 4;104(1):144-158
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory