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Elmod1 Gene Detail
Summary
  • Symbol
    Elmod1
  • Name
    ELMO/CED-12 domain containing 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3583900
    NCBI Gene: 270162
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:53818741-53882585 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1845 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3583900
 protein coding gene Chr9:53818741-53882628 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034819
 protein coding gene Chr9:52954021-53014509 (-)
A/J MGP_AJ_G0034800
 protein coding gene Chr9:51279279-51337379 (-)
AKR/J MGP_AKRJ_G0034728
 protein coding gene Chr9:52409601-52470034 (-)
BALB/cJ MGP_BALBcJ_G0034792
 protein coding gene Chr9:51030407-51091931 (-)
C3H/HeJ MGP_C3HHeJ_G0034502
 protein coding gene Chr9:52882379-52943138 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035311
 protein coding gene Chr9:54455153-54520551 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032223
 protein coding gene Chr9:50678437-50736708 (-)
CAST/EiJ MGP_CASTEiJ_G0033824
 protein coding gene Chr9:52882908-52948292 (-)
CBA/J MGP_CBAJ_G0034473
 protein coding gene Chr9:56298179-56370354 (-)
DBA/2J MGP_DBA2J_G0034632
 protein coding gene Chr9:51154256-51211636 (-)
FVB/NJ MGP_FVBNJ_G0034574
 protein coding gene Chr9:50339917-50397944 (-)
LP/J MGP_LPJ_G0034714
 protein coding gene Chr9:53262690-53323995 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034617
 protein coding gene Chr9:57887267-57950136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035333
 protein coding gene Chr9:52411910-52476279 (-)
PWK/PhJ MGP_PWKPhJ_G0033528
 protein coding gene Chr9:51128426-51191513 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033363
 protein coding gene Chr9:52673044-52733719 (-)
WSB/EiJ MGP_WSBEiJ_G0033936
 protein coding gene Chr9:52399668-52458557 (-)



Homology
more
  • Human Ortholog
    ELMOD1, ELMO domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELMOD1, ELMO domain containing 1
  • Links
    NCBI Gene ID: 55531
    neXtProt AC: NX_Q8N336
    UniProt: Q8N336

  • Chr Location
    11q22.3; chr11:107591091-107666779 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    48 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotypes from multigenic genotypes
    2 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous allele exhibit circling, absent startle reflex, deafness, organ of Corti degeneration and abnormal cochlear hair stereociliary bundle.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    850
  • Tissues
    42
  • cDNA Data
    8
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041986 Ensembl Gene Model | MGI Sequence Detail 63845 C57BL/6J ±  kb
    transcript ENSMUST00000048409 Ensembl | MGI Sequence Detail 2605 Not Applicable  
    polypeptide ENSMUSP00000046191 Ensembl | MGI Sequence Detail 326 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 8
      Primer pair 3

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2143043, MGI:2143123
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 5
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory