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Ldlrad2 Gene Detail
Summary
  • Symbol
    Ldlrad2
  • Name
    low density lipoprotein receptor class A domain containing 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588210
    NCBI Gene: 435811
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:137298187-137309415 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 69.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    360 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588210
 protein coding gene Chr4:137298185-137309429 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028984
 protein coding gene Chr4:140218427-140220662 (-)
A/J MGP_AJ_G0028943
 protein coding gene Chr4:134254961-134257452 (-)
AKR/J MGP_AKRJ_G0028895
 protein coding gene Chr4:138105414-138107905 (-)
BALB/cJ MGP_BALBcJ_G0028967
 protein coding gene Chr4:134932248-134934740 (-)
C3H/HeJ MGP_C3HHeJ_G0028681
 protein coding gene Chr4:138443875-138446367 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029408
 protein coding gene Chr4:145221224-145223675 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026679
 protein coding gene Chr4:127261414-127263735 (-)
CAST/EiJ MGP_CASTEiJ_G0028113
 protein coding gene Chr4:136581708-136584191 (-)
CBA/J MGP_CBAJ_G0028646
 protein coding gene Chr4:149304175-149306667 (-)
DBA/2J MGP_DBA2J_G0028795
 protein coding gene Chr4:134644422-134646909 (-)
FVB/NJ MGP_FVBNJ_G0028762
 protein coding gene Chr4:133642668-133645160 (-)
LP/J MGP_LPJ_G0028894
 protein coding gene Chr4:140310482-140312716 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028788
 protein coding gene Chr4:153343736-153346698 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029446
 protein coding gene Chr4:138584678-138586912 (-)
PWK/PhJ MGP_PWKPhJ_G0027833
 protein coding gene Chr4:131466892-131469617 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027659
 protein coding gene Chr4:134364413-134366752 (-)
WSB/EiJ MGP_WSBEiJ_G0028191
 protein coding gene Chr4:138787015-138789494 (-)



Homology
more
  • Human Ortholog
    LDLRAD2, low density lipoprotein receptor class A domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LDLRAD2, low density lipoprotein receptor class A domain containing 2
  • Links
    NCBI Gene ID: 401944
    neXtProt AC: NX_Q5SZI1
    UniProt: Q5SZI1

  • Chr Location
    1p36.12; chr1:21812265-21825225 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000094035 Ensembl Gene Model | MGI Sequence Detail 11229 C57BL/6J ±  kb
transcript ENSMUST00000238941 Ensembl | MGI Sequence Detail 1183 Not Applicable  
polypeptide ENSMUSP00000158970 Ensembl | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR036055 LDL receptor-like superfamily
    IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
    IPR042333 Low-density lipoprotein receptor class A domain-containing protein 2
    IPR035914 Spermadhesin, CUB domain superfamily
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Phenotypes 5
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory