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Magea10 Gene Detail
Summary
  • Symbol
    Magea10
  • Name
    MAGE family member A10
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588211
    NCBI Gene: 236852
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:71425476-71430464 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588211
 protein coding gene ChrX:71425476-71430464 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035792
 protein coding gene ChrX:68072108-68077096 (-)
A/J MGP_AJ_G0035776
 protein coding gene ChrX:68288353-68293294 (-)
AKR/J MGP_AKRJ_G0035698
 protein coding gene ChrX:70133841-70138829 (-)
BALB/cJ MGP_BALBcJ_G0035763
 protein coding gene ChrX:67316805-67321793 (-)
C3H/HeJ MGP_C3HHeJ_G0035466
 protein coding gene ChrX:68570964-68575952 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036293
 protein coding gene ChrX:70150216-70155204 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033140
 protein coding gene ChrX:67471937-67476930 (-)
CAST/EiJ MGP_CASTEiJ_G0034758
 protein coding gene ChrX:53930391-53935343 (-)
CBA/J MGP_CBAJ_G0035441
 protein coding gene ChrX:72063794-72068782 (-)
DBA/2J MGP_DBA2J_G0035594
 protein coding gene ChrX:67770606-67775594 (-)
FVB/NJ MGP_FVBNJ_G0035545
 protein coding gene ChrX:67117559-67122547 (-)
LP/J MGP_LPJ_G0035683
 protein coding gene ChrX:68914198-68919186 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035580
 protein coding gene ChrX:74653969-74658957 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036314
 protein coding gene ChrX:67929595-67934583 (-)
PWK/PhJ MGP_PWKPhJ_G0034458
 protein coding gene ChrX:51944235-51949332 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034293
 protein coding gene ChrX:54837324-54842305 (-)
WSB/EiJ MGP_WSBEiJ_G0034900
 protein coding gene ChrX:67244248-67249236 (-)



Homology
more
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Vertebrate Orthologs
    8
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Synonyms
    CT1.10, MAGE10
  • Links
    NCBI Gene ID: 4109
    neXtProt AC: NX_P43363
    UniProt: P43363

  • Chr Location
    Xq28; chrX:152133310-152138578 (-)  GRCh38
  • Human Ortholog
    MAGEA12, MAGE family member A12
  • Synonyms
    CT1.12, MAGE12
  • Links
    NCBI Gene ID: 4111
    neXtProt AC: NX_P43365
    UniProt: P43365

  • Chr Location
    Xq28; chrX:152733757-152737669 (+)  GRCh38
  • Human Ortholog
    MAGEA2, MAGE family member A2
  • Synonyms
    CT1.2, MAGE2, MAGEA2A
  • Links
    NCBI Gene ID: 4101
    neXtProt AC: NX_P43356
    UniProt: P43356

  • Chr Location
    Xq28
  • Human Ortholog
    MAGEA2B, MAGE family member A2B
  • Synonyms
    CT1.2, MAGE2
  • Links
    NCBI Gene ID: 266740
    neXtProt AC: NX_P43356
    UniProt: P43356

  • Chr Location
    Xq28; chrX:152714586-152718607 (+)  GRCh38
  • Human Ortholog
    MAGEA4, MAGE family member A4
  • Synonyms
    CT1.4, MAGE4, MAGE-41, MAGE4A, MAGE4B, MAGE-X2
  • Links
    NCBI Gene ID: 4103
    neXtProt AC: NX_P43358
    UniProt: P43358

  • Chr Location
    Xq28; chrX:151912474-151925171 (+)  GRCh38
  • Human Ortholog
    MAGEA8, MAGE family member A8
  • Synonyms
    CT1.8, MAGE8
  • Links
    NCBI Gene ID: 4107
    neXtProt AC: NX_P43361
    UniProt: P43361

  • Chr Location
    Xq28; chrX:149881141-149885835 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    28
  • cDNA Data
    6
  • Literature Summary
    9
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 236852 NCBI Gene Model | MGI Sequence Detail 4989 C57BL/6J ±  kb
transcript NM_001085506 RefSeq | MGI Sequence Detail 1821 C57BL/6  
polypeptide NP_001078975 RefSeq | MGI Sequence Detail 325 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
    IPR021072 Melanoma associated antigen, N-terminal
Molecular
Reagents
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  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 9
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory