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Clec4b2 Gene Detail
Summary
  • Symbol
    Clec4b2
  • Name
    C-type lectin domain family 4, member b2
  • Synonyms
    F830043G12Rik, mDCAR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588267
    NCBI Gene: 381809
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:123149852-123181630 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 58.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    925 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588267
 protein coding gene Chr6:123149827-123181630 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031241
 protein coding gene Chr6:126314162-126351942 (+)
A/J MGP_AJ_G0031210
 protein coding gene Chr6:121488710-121526964 (+)
AKR/J MGP_AKRJ_G0031140
 protein coding gene Chr6:124871656-124905608 (+)
BALB/cJ MGP_BALBcJ_G0031220
 protein coding gene Chr6:121215878-121252754 (+)
C3H/HeJ MGP_C3HHeJ_G0030939
 protein coding gene Chr6:124818213-124861325 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031679
 protein coding gene Chr6:129640145-129676423 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028835
 protein coding gene Chr6:118065656-118096256 (+)
CAST/EiJ MGP_CASTEiJ_G0030328
 protein coding gene Chr6:125083839-125110110 (+)
CBA/J MGP_CBAJ_G0030902
 protein coding gene Chr6:134713382-134747764 (+)
DBA/2J MGP_DBA2J_G0031058
 protein coding gene Chr6:120446787-120479144 (+)
FVB/NJ MGP_FVBNJ_G0031010
 protein coding gene Chr6:119377992-119414286 (+)
LP/J MGP_LPJ_G0031139
 protein coding gene Chr6:126484990-126526445 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031046
 protein coding gene Chr6:138640106-138675416 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031708
 protein coding gene Chr6:124756602-124793005 (+)
PWK/PhJ MGP_PWKPhJ_G0030042
 protein coding gene Chr6:119270816-119301004 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029870
 protein coding gene Chr6:122890502-122924898 (+)
WSB/EiJ MGP_WSBEiJ_G0030410
 protein coding gene Chr6:125062803-125095094 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067767 Ensembl Gene Model | MGI Sequence Detail 31779 C57BL/6J ±  kb
transcript ENSMUST00000088455 Ensembl | MGI Sequence Detail 1174 Not Applicable  
polypeptide ENSMUSP00000085802 Ensembl | MGI Sequence Detail 208 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR033989 CD209-like, C-type lectin-like domain
    IPR050111 C-type lectin and snaclec domain-containing protein
    IPR018378 C-type lectin, conserved site
    IPR016187 C-type lectin fold
    IPR001304 C-type lectin-like
    IPR016186 C-type lectin-like/link domain superfamily
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:93065 Flornes LM, et al., Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. Immunogenetics. 2004 Oct;56(7):506-17
  • Latest
    J:293130 Backdahl L, et al., Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease. PLoS Genet. 2020 Jun;16(6):e1008788
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory