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Tmem120b Gene Detail
Summary
  • Symbol
    Tmem120b
  • Name
    transmembrane protein 120B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3603158
    NCBI Gene: 330189
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:123214329-123256272 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1117 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3603158
 protein coding gene Chr5:123206478-123256272 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030063
 protein coding gene Chr5:126749600-126803015 (+)
A/J MGP_AJ_G0030028
 protein coding gene Chr5:121502409-121551452 (+)
AKR/J MGP_AKRJ_G0029964
 protein coding gene Chr5:125409886-125458627 (+)
BALB/cJ MGP_BALBcJ_G0030039
 protein coding gene Chr5:122835643-122885772 (+)
C3H/HeJ MGP_C3HHeJ_G0029756
 protein coding gene Chr5:126036126-126084868 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030492
 protein coding gene Chr5:131638344-131695819 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027718
 protein coding gene Chr5:116086307-116135103 (+)
CAST/EiJ MGP_CASTEiJ_G0029165
 protein coding gene Chr5:125134870-125193575 (+)
CBA/J MGP_CBAJ_G0029726
 protein coding gene Chr5:136803300-136858815 (+)
DBA/2J MGP_DBA2J_G0029876
 protein coding gene Chr5:121548512-121597434 (+)
FVB/NJ MGP_FVBNJ_G0029832
 protein coding gene Chr5:120548004-120598742 (+)
LP/J MGP_LPJ_G0029965
 protein coding gene Chr5:127284151-127337358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029863
 protein coding gene Chr5:140489549-140543443 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030533
 protein coding gene Chr5:125008970-125061941 (+)
PWK/PhJ MGP_PWKPhJ_G0028879
 protein coding gene Chr5:120334502-120384434 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028716
 protein coding gene Chr5:122708586-122759981 (+)
WSB/EiJ MGP_WSBEiJ_G0029240
 protein coding gene Chr5:125675621-125730031 (+)



Homology
more
  • Human Ortholog
    TMEM120B, transmembrane protein 120B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM120B, transmembrane protein 120B
  • Links
    NCBI Gene ID: 144404
    neXtProt AC: NX_A0PK00
    UniProt: A0PK00

  • Chr Location
    12q24.31; chr12:121712752-121783001 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmem120b
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    24 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    32
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 330189 NCBI Gene Model | MGI Sequence Detail 41944 C57BL/6J ±  kb
transcript NR_185160 RefSeq | MGI Sequence Detail 2685 C57BL/6  
polypeptide Q3TA38 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 32

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory