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BC049715 Gene Detail
Summary
  • Symbol
    BC049715
  • Name
    cDNA sequence BC049715
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605234
    NCBI Gene: 320135
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136804624-136817660 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    750 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3605234
 protein coding gene Chr6:136804624-136818918 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031427
 protein coding gene Chr6:141289783-141323076 (+)
A/J MGP_AJ_G0031403
 protein coding gene Chr6:135679913-135733223 (+)
AKR/J MGP_AKRJ_G0031331
 protein coding gene Chr6:139820358-139866092 (+)
BALB/cJ MGP_BALBcJ_G0031410
 protein coding gene Chr6:135562405-135599384 (+)
C3H/HeJ MGP_C3HHeJ_G0031131
 protein coding gene Chr6:139857048-139894865 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031871
 protein coding gene Chr6:145169313-145182270 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029001
 protein coding gene Chr6:134835391-134848522 (+)
CAST/EiJ MGP_CASTEiJ_G0030500
 protein coding gene Chr6:139368167-139394550 (+)
CBA/J MGP_CBAJ_G0031091
 protein coding gene Chr6:150559958-150619520 (+)
DBA/2J MGP_DBA2J_G0031248
 protein coding gene Chr6:134572471-134608932 (+)
FVB/NJ MGP_FVBNJ_G0031199
 protein coding gene Chr6:133475242-133509024 (+)
LP/J MGP_LPJ_G0031332
 protein coding gene Chr6:141411572-141445990 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031239
 protein coding gene Chr6:154452283-154503534 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031903
 protein coding gene Chr6:139577053-139609252 (+)
PWK/PhJ MGP_PWKPhJ_G0030226
 protein coding gene Chr6:133082098-133104604 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030050
 protein coding gene Chr6:137848586-137873048 (+)
WSB/EiJ MGP_WSBEiJ_G0030592
 protein coding gene Chr6:140219328-140243408 (+)



Homology
more
  • Human Ortholog
    C12orf60, chromosome 12 open reading frame 60
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C12orf60, chromosome 12 open reading frame 60
  • Links
    NCBI Gene ID: 144608
    neXtProt AC: NX_Q5U649
    UniProt: Q5U649

  • Chr Location
    12p12.3; chr12:14803666-14906586 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047515 Ensembl Gene Model | MGI Sequence Detail 13037 C57BL/6J ±  kb
    transcript ENSMUST00000052702 Ensembl | MGI Sequence Detail 1120 Not Applicable  
    polypeptide ENSMUSP00000049512 Ensembl | MGI Sequence Detail 247 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 1
    References
    more
    • Summaries
      All 21
      Phenotypes 8
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory