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Hexd Gene Detail
Summary
  • Symbol
    Hexd
  • Name
    hexosaminidase D
  • Synonyms
    Hexdc
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605542
    NCBI Gene: 238023
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121095259-121113481 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 85.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    511 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3605542
 protein coding gene Chr11:121095187-121113485 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019542
 protein coding gene Chr11:125742934-125759102 (+)
A/J MGP_AJ_G0019509
 protein coding gene Chr11:120123759-120140902 (+)
AKR/J MGP_AKRJ_G0019479
 protein coding gene Chr11:123763598-123781686 (+)
BALB/cJ MGP_BALBcJ_G0019484
 protein coding gene Chr11:120495215-120511343 (+)
C3H/HeJ MGP_C3HHeJ_G0019290
 protein coding gene Chr11:124089269-124106146 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019933
 protein coding gene Chr11:129555400-129573756 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017558
 protein coding gene Chr11:117110305-117125889 (+)
CAST/EiJ MGP_CASTEiJ_G0018844
 protein coding gene Chr11:125593674-125611847 (+)
CBA/J MGP_CBAJ_G0019261
 protein coding gene Chr11:134590904-134607122 (+)
DBA/2J MGP_DBA2J_G0019374
 protein coding gene Chr11:119494610-119511680 (+)
FVB/NJ MGP_FVBNJ_G0019365
 protein coding gene Chr11:119210729-119229870 (+)
LP/J MGP_LPJ_G0019445
 protein coding gene Chr11:126019258-126037871 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019398
 protein coding gene Chr11:133402515-133421794 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019972
 protein coding gene Chr11:124442339-124462726 (+)
PWK/PhJ MGP_PWKPhJ_G0018611
 protein coding gene Chr11:120938752-120954894 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018402
 protein coding gene Chr11:124199507-124219310 (+)
WSB/EiJ MGP_WSBEiJ_G0018897
 protein coding gene Chr11:124418536-124435293 (+)



Homology
more
  • Human Ortholog
    HEXD, hexosaminidase D
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HEXD, hexosaminidase D
  • Synonyms
    HEXDC
  • Links
    NCBI Gene ID: 284004
    neXtProt AC: NX_Q8WVB3
    UniProt: Q8WVB3

  • Chr Location
    17q25.3; chr17:82418318-82442645 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039307 Ensembl Gene Model | MGI Sequence Detail 18223 C57BL/6J ±  kb
transcript ENSMUST00000038831 Ensembl | MGI Sequence Detail 2378 Not Applicable  
polypeptide ENSMUSP00000048479 Ensembl | MGI Sequence Detail 559 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 2
Other
Accession IDs
less
MGI:7488150
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:149083 Gutternigg M, et al., Mammalian cells contain a second nucleocytoplasmic hexosaminidase. Biochem J. 2009 Apr 1;419(1):83-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory