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Fam222a Gene Detail
Summary
  • Symbol
    Fam222a
  • Name
    family with sequence similarity 222, member A
  • Synonyms
    BC057022
  • Feature Type
    protein coding gene
  • IDs
    MGI:3605543
    NCBI Gene: 433940
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:114706312-114751281 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 55.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1231 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3605543
 protein coding gene Chr5:114706077-114751281 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029940
 protein coding gene Chr5:117329967-117377010 (+)
A/J MGP_AJ_G0029905
 protein coding gene Chr5:112706922-112751694 (+)
AKR/J MGP_AKRJ_G0029843
 protein coding gene Chr5:116281589-116328499 (+)
BALB/cJ MGP_BALBcJ_G0029916
 protein coding gene Chr5:114074210-114119480 (+)
C3H/HeJ MGP_C3HHeJ_G0029636
 protein coding gene Chr5:116789165-116837330 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030370
 protein coding gene Chr5:121853565-121904253 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027598
 protein coding gene Chr5:107529733-107577178 (+)
CAST/EiJ MGP_CASTEiJ_G0029044
 protein coding gene Chr5:115731666-115776634 (+)
CBA/J MGP_CBAJ_G0029603
 protein coding gene Chr5:126506583-126559491 (+)
DBA/2J MGP_DBA2J_G0029753
 protein coding gene Chr5:112775633-112822071 (+)
FVB/NJ MGP_FVBNJ_G0029710
 protein coding gene Chr5:111582753-111628270 (+)
LP/J MGP_LPJ_G0029842
 protein coding gene Chr5:117890981-117943622 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029741
 protein coding gene Chr5:130913736-130959860 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030411
 protein coding gene Chr5:115758139-115806386 (+)
PWK/PhJ MGP_PWKPhJ_G0028758
 protein coding gene Chr5:111426251-111472485 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028596
 protein coding gene Chr5:113296752-113351590 (+)
WSB/EiJ MGP_WSBEiJ_G0029120
 protein coding gene Chr5:116339443-116391275 (+)



Homology
more
  • Human Ortholog
    FAM222A, family with sequence similarity 222 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM222A, family with sequence similarity 222 member A
  • Synonyms
    C12orf34
  • Links
    NCBI Gene ID: 84915
    neXtProt AC: NX_Q5U5X8
    UniProt: Q5U5X8

  • Chr Location
    12q24.11; chr12:109713825-109770495 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • cDNA Data
    5
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 433940 NCBI Gene Model | MGI Sequence Detail 44970 C57BL/6J ±  kb
    transcript NM_001004180 RefSeq | MGI Sequence Detail 2717 C57BL/6  
    polypeptide Q6PGH4 UniProt | EBI | MGI Sequence Detail 453 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 5
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Phenotypes 13
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory