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H2aj Gene Detail
Summary
  • Symbol
    H2aj
  • Name
    H2J.A histone
  • Synonyms
    E130307C13, H2afj
  • Feature Type
    protein coding gene
  • IDs
    MGI:3606192
    NCBI Gene: 232440
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136785246-136787072 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3606192
 protein coding gene Chr6:136785242-136787072 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031425
 protein coding gene Chr6:141268699-141270532 (+)
A/J MGP_AJ_G0031401
 protein coding gene Chr6:135658307-135660139 (+)
AKR/J MGP_AKRJ_G0031328
 protein coding gene Chr6:139794130-139795962 (+)
BALB/cJ MGP_BALBcJ_G0031408
 protein coding gene Chr6:135538295-135540132 (+)
C3H/HeJ MGP_C3HHeJ_G0031129
 protein coding gene Chr6:139823620-139825452 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031869
 protein coding gene Chr6:145146294-145148124 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028999
 protein coding gene Chr6:134817068-134818909 (+)
CAST/EiJ MGP_CASTEiJ_G0030498
 protein coding gene Chr6:139349546-139351372 (+)
CBA/J MGP_CBAJ_G0031089
 protein coding gene Chr6:150540002-150541834 (+)
DBA/2J MGP_DBA2J_G0031246
 protein coding gene Chr6:134553517-134555349 (+)
FVB/NJ MGP_FVBNJ_G0031197
 protein coding gene Chr6:133445457-133448440 (+)
LP/J MGP_LPJ_G0031330
 protein coding gene Chr6:141386566-141388399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031237
 protein coding gene Chr6:154430400-154432232 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031901
 protein coding gene Chr6:139558187-139560024 (+)
PWK/PhJ MGP_PWKPhJ_G0030224
 protein coding gene Chr6:133063416-133065276 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030048
 protein coding gene Chr6:137827287-137832164 (+)
WSB/EiJ MGP_WSBEiJ_G0030590
 protein coding gene Chr6:140186367-140188203 (+)



Homology
more
  • Human Ortholog
    H2AJ, H2A.J histone
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2AJ, H2A.J histone
  • Synonyms
    H2AFJ
  • Links
    NCBI Gene ID: 55766
    neXtProt AC: NX_Q9BTM1
    UniProt: Q9BTM1

  • Chr Location
    12p12.3; chr12:14774405-14778002 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    88
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232440 NCBI Gene Model | MGI Sequence Detail 1827 C57BL/6J ±  kb
transcript NM_177688 RefSeq | MGI Sequence Detail 1827 C57BL/6  
polypeptide Q8R1M2 UniProt | EBI | MGI Sequence Detail 129 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 89
    cDNA 88
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:6358818
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:343536 Rube CE, et al., Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis. NPJ Aging Mech Dis. 2021 Apr 1;7(1):7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory