Colec10 MGI Mouse Gene Detail - MGI:3606482 - collectin sub-family member 10

Symbol

Colec10
Name

collectin sub-family member 10
Synonyms

CL-L1

Feature Type

protein coding gene
IDs

MGI:3606482
NCBI Gene: 239447
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr15:54274170-54329754 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 21.15 cM
Mapping Data

1 experiment

SNPs within 2kb

1479 from dbSNP Build 142
Strain Annotations

18
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3606482	protein coding gene	Chr15:54274170-54329755 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021847	protein coding gene	Chr15:53460864-53511659 (+)
A/J	MGP_AJ_G0021807	protein coding gene	Chr15:51340501-51390214 (+)
AKR/J	MGP_AKRJ_G0021788	protein coding gene	Chr15:52786160-52840529 (+)
BALB/cJ	MGP_BALBcJ_G0021814	protein coding gene	Chr15:51565812-51618796 (+)
C3H/HeJ	MGP_C3HHeJ_G0021588	protein coding gene	Chr15:52875989-52927352 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022253	protein coding gene	Chr15:55560398-55613420 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019790	protein coding gene	Chr15:48608086-48660216 (+)
CAST/EiJ	MGP_CASTEiJ_G0021105	protein coding gene	Chr15:53444154-53496852 (+)
CBA/J	MGP_CBAJ_G0021557	protein coding gene	Chr15:57532457-57594394 (+)
DBA/2J	MGP_DBA2J_G0021681	protein coding gene	Chr15:51227932-51277268 (+)
FVB/NJ	MGP_FVBNJ_G0021659	protein coding gene	Chr15:50370617-50421748 (+)
LP/J	MGP_LPJ_G0021751	protein coding gene	Chr15:53268909-53319042 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021683	protein coding gene	Chr15:62611164-62670468 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022276	protein coding gene	Chr15:53141709-53195923 (+)
PWK/PhJ	MGP_PWKPhJ_G0020850	protein coding gene	Chr15:51305726-51355546 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020687	protein coding gene	Chr15:52875603-52925853 (+)
WSB/EiJ	MGP_WSBEiJ_G0021160	protein coding gene	Chr15:53124565-53181409 (+)

Human Ortholog

COLEC10, collectin subfamily member 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COLEC10, collectin subfamily member 10
Synonyms

3MC3, CL-10, CL-34, CLL1
Links

HGNC:2220

NCBI Gene ID: 10584

neXtProt AC: NX_Q9Y6Z7

UniProt: Q9Y6Z7
Chr Location

8q24.12; chr8:118952263-119108455 (+) GRCh38

MGI Vertebrate Homology

Colec10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: COLEC10
Gene Tree

Colec10

Diseases

1 with human COLEC10 associations

				Human Disease	Mouse Models
				3MC syndrome 3 IDs 3MC syndrome 3 DOID:0060577 OMIM:248340

Click on a disease name to see all genes associated with that disease.

References

1 with disease annotations

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Phenotype Summary

9 phenotypes from 1 allele in 1 genetic background
19 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

3
Endonuclease-mediated

4
Radiation induced

1
Targeted

1
Genomic Mutations

4 involving Colec10
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

27 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

23
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

735
Tissues

25
cDNA Data

6
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas
Other Vertebrate Links

Xenbase colec10

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All Sequences

35
RefSeq

6
UniProt

1
CCDS

CCDS27469.1

Ensembl

ENSMUSG00000038591 (Evidence)
NCBI Gene

239447

			Length	Strain/Species	Flank
genomic	ENSMUSG00000038591	Ensembl Gene Model \| MGI Sequence Detail	55585	C57BL/6J	± kb
transcript	ENSMUST00000036737	Ensembl \| MGI Sequence Detail	4587	Not Applicable
polypeptide	ENSMUSP00000037867	Ensembl \| MGI Sequence Detail	277	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000005725 collectin-10

(term hierarchy)
InterPro Domains

IPR050801 Calcium-Dependent Lectins in Immunity and Development

IPR008160 Collagen triple helix repeat

IPR033990 Collectin, C-type lectin-like domain

IPR018378 C-type lectin, conserved site

IPR016187 C-type lectin fold

IPR001304 C-type lectin-like

IPR016186 C-type lectin-like/link domain superfamily
GlyGen

Q8CF98 2 sites

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All nucleic 7

cDNA 6

Primer pair 1

Microarray probesets 2

Summaries

All 38

Developmental Gene Expression 1

Diseases 1

Gene Ontology 7

Phenotypes 19
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Colec10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr131264	Chr15:54274043-54274060 (+)	-118 bp
Tssr131265	Chr15:54274063-54274074 (+)	-101 bp
Tssr131266	Chr15:54274131-54274144 (+)	-32 bp
Tssr131267	Chr15:54274151-54274193 (+)	2 bp
Tssr131268	Chr15:54274204-54274217 (+)	41 bp
Tssr131269	Chr15:54298407-54298412 (+)	24,240 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24