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Gdpd4 Gene Detail
Summary
  • Symbol
    Gdpd4
  • Name
    glycerophosphodiester phosphodiesterase domain containing 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:3606573
    NCBI Gene: 233537
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:97569162-97698870 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3602 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3606573
protein coding gene Chr7:97569151-97698870 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032532
protein coding gene Chr7:100645895-100769310 (+)
A/J MGP_AJ_G0032506
protein coding gene Chr7:98138208-98284515 (+)
AKR/J MGP_AKRJ_G0032442
protein coding gene Chr7:100481949-100620030 (+)
BALB/cJ MGP_BALBcJ_G0032517
protein coding gene Chr7:97836688-97971629 (+)
C3H/HeJ MGP_C3HHeJ_G0032232
protein coding gene Chr7:100842660-100970368 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033015
protein coding gene Chr7:104553761-104683692 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030010
protein coding gene Chr7:100590513-100732022 (+)
CAST/EiJ MGP_CASTEiJ_G0031559
protein coding gene Chr7:92360318-92481713 (+)
CBA/J MGP_CBAJ_G0032199
protein coding gene Chr7:108090301-108221259 (+)
DBA/2J MGP_DBA2J_G0032351
protein coding gene Chr7:96500496-96615857 (+)
FVB/NJ MGP_FVBNJ_G0032307
protein coding gene Chr7:96286552-96417833 (+)
LP/J MGP_LPJ_G0032440
protein coding gene Chr7:101963986-102091936 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032340
protein coding gene Chr7:109641727-109777606 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033037
protein coding gene Chr7:99770606-99889518 (+)
PWK/PhJ MGP_PWKPhJ_G0031277
protein coding gene Chr7:89562518-89685712 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031120
protein coding gene Chr7:87013198-87156568 (+)
WSB/EiJ MGP_WSBEiJ_G0031676
protein coding gene Chr7:100410601-100529733 (+)



Homology
more
  • Human Ortholog
    GDPD4, glycerophosphodiester phosphodiesterase domain containing 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GDPD4, glycerophosphodiester phosphodiesterase domain containing 4
  • Synonyms
    GDE6
  • Links
    NCBI Gene ID: 220032
    neXtProt AC: NX_Q6W3E5
    UniProt: Q6W3E5

  • Chr Location
    11q13.5; chr11:77216558-77301699 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035582 Ensembl Gene Model | MGI Sequence Detail 129709 C57BL/6J ±  kb
transcript ENSMUST00000041860 Ensembl | MGI Sequence Detail 3053 Not Applicable  
polypeptide ENSMUSP00000036772 Ensembl | MGI Sequence Detail 632 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000031515 glycerophosphodiester phosphodiesterase domain-containing protein 4
  • EC
  • InterPro Domains
    IPR030395 Glycerophosphodiester phosphodiesterase domain
    IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
  • GlyGen
    Q3TT99 4 sites
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:279308 Fujihara Y, et al., Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18498-18506

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory