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Dnaaf6 Gene Detail
Summary
  • Symbol
    Dnaaf6
  • Name
    dynein axonemal assembly factor 6
  • Synonyms
    Dnaaf6b, E230019M04Rik, Pih1h3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:3607720
    NCBI Gene: 331537
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:138963628-139007546 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 61.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    746 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3607720
 protein coding gene ChrX:138963628-139007546 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036132
 protein coding gene ChrX:137588483-137633207 (+)
A/J MGP_AJ_G0036110
 protein coding gene ChrX:136975691-137020262 (+)
AKR/J MGP_AKRJ_G0036035
 protein coding gene ChrX:141360573-141413461 (+)
BALB/cJ MGP_BALBcJ_G0036100
 protein coding gene ChrX:135302737-135346649 (+)
C3H/HeJ MGP_C3HHeJ_G0035809
 protein coding gene ChrX:137611958-137657518 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036625
 protein coding gene ChrX:141632732-141679370 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033449
 protein coding gene ChrX:128705320-128747897 (+)
CAST/EiJ MGP_CASTEiJ_G0035100
 protein coding gene ChrX:118417541-118461860 (+)
CBA/J MGP_CBAJ_G0035786
 protein coding gene ChrX:145960528-146005818 (+)
DBA/2J MGP_DBA2J_G0035943
 protein coding gene ChrX:136130696-136175220 (+)
FVB/NJ MGP_FVBNJ_G0035877
 protein coding gene ChrX:135365318-135410255 (+)
LP/J MGP_LPJ_G0036034
 protein coding gene ChrX:138549934-138594225 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035914
 protein coding gene ChrX:153498580-153549472 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036661
 protein coding gene ChrX:136902024-136944819 (+)
PWK/PhJ MGP_PWKPhJ_G0034793
 protein coding gene ChrX:115332376-115375625 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034619
 protein coding gene ChrX:118949436-118996225 (+)
WSB/EiJ MGP_WSBEiJ_G0035235
 protein coding gene ChrX:135229469-135273264 (+)



Homology
more
  • Human Ortholog
    DNAAF6, dynein axonemal assembly factor 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAAF6, dynein axonemal assembly factor 6
  • Synonyms
    CILD36, CXorf41, NYSAR97, PIH1D3, TWISTER
  • Links
    NCBI Gene ID: 139212
    neXtProt AC: NX_Q9NQM4
    UniProt: Q9NQM4

  • Chr Location
    Xq22.3; chrX:107206611-107244247 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DNAAF6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    9
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 331537 NCBI Gene Model | MGI Sequence Detail 43919 C57BL/6J ±  kb
transcript NM_177921 RefSeq | MGI Sequence Detail 1509 C57BL/6  
polypeptide NP_808589 RefSeq | MGI Sequence Detail 218 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026697 Dynein axonemal assembly factor 6
    IPR041442 PIH1D1/2/3, CS-like domain
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:6390568, MGI:7519134
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory